SCHEMBL3445969

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3446122	0.86	GRIN1 (0.73)	GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
	SCHEMBL3446674	0.83	GRIN1 (0.74)	GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
	Hydrochloric Acid SCHEMBL4577735	0.82	GRIN1 (0.73)	GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
	SCHEMBL4577962	0.79	GRIN2D (0.59)	GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
	SCHEMBL14040639	0.78	GRIN1 (0.52)	GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
	SCHEMBL16239879	0.76	ENPP2 (0.59)	GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
	SCHEMBL4577408	0.76	ALDH1A1 (0.61)	GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
	SCHEMBL4418438	0.76	GRIN2D (0.61)	GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
	SCHEMBL3454623	0.76	GRIN1 (0.60)	GRIN1GRIN2DGRIN3BGRIN2AGRIN2B
	SCHEMBL3445998	0.74	GRIN2D (0.73)	GRIN1GRIN2DGRIN3BGRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.