SCHEMBL34461090

SCHEMBL34461090

CC(C)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)O)C(C)C

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ DPP3 Q9NY33 5/20 0.59
▸ IL23R Q5VWK5 1/20 0.55
▸ KISS1R Q969F8 5/20 0.54
▸ C5AR1 P21730 1/20 0.54
▸ CXCR4 P61073 1/20 0.52
▸ EPHA2 P29317 1/20 0.51
▸ TACR2 P21452 2/20 0.51
▸ MC4R P32245 2/20 0.51
▸ MC5R P33032 2/20 0.51
▸ MC3R P41968 2/20 0.51
▸ MC1R Q01726 2/20 0.51
▸ CTSL P07711 2/20 0.50
▸ CTSS P25774 2/20 0.50
▸ CTSK P43235 2/20 0.50
▸ CTSH P09668 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34461111 0.98 DPP3 (0.56) DPP3IL23RKISS1RC5AR1CXCR4
SCHEMBL34461114 0.95 DPP3 (0.55) DPP3IL23RKISS1RC5AR1CXCR4
SCHEMBL34461093 0.94 KISS1R (0.57) DPP3IL23RKISS1RC5AR1CXCR4
SCHEMBL34461110 0.93 DPP3 (0.53) DPP3IL23RKISS1RC5AR1CXCR4
SCHEMBL34461097 0.92 CXCR4 (0.59) DPP3IL23RKISS1RC5AR1CXCR4
SCHEMBL34461092 0.91 CXCR4 (0.59) DPP3KISS1RC5AR1CXCR4
SCHEMBL31620052 0.90 C5AR1 (0.57) DPP3IL23RKISS1RC5AR1CXCR4
SCHEMBL31001650 0.89 CXCR4 (0.61) DPP3IL23RC5AR1CXCR4MC4R
SCHEMBL34461077 0.89 CXCR4 (0.58) DPP3IL23RKISS1RC5AR1CXCR4
SCHEMBL31430442 0.88 C5AR1 (0.62) DPP3IL23RKISS1RC5AR1EPHA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098072-A1 METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS ENDEVICA BIO INC (US) 2026-04-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098072-A1 METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS MC1R, MC4R, MC5R DPP3 359/4885IL23R 831/4885KISS1R 154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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