SCHEMBL34461092

SCHEMBL34461092

CC(C)C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)O)C(C)C

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CXCR4 P61073 10/20 0.59
▸ NTSR2 O95665 1/20 0.55
▸ NTSR1 P30989 1/20 0.55
▸ SORT1 Q99523 1/20 0.55
▸ KISS1R Q969F8 4/20 0.54
▸ CAPN1 P07384 2/20 0.53
▸ CTSB P07858 2/20 0.53
▸ DPP3 Q9NY33 1/20 0.52
▸ C5AR1 P21730 1/20 0.51
▸ F13A1 P00488 1/20 0.51
▸ TGM2 P21980 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34461093 0.98 KISS1R (0.57) CXCR4NTSR2NTSR1SORT1KISS1R
SCHEMBL34461111 0.93 DPP3 (0.56) CXCR4NTSR2NTSR1SORT1KISS1R
SCHEMBL31290071 0.92 CXCR4 (0.61) CXCR4NTSR2NTSR1SORT1KISS1R
SCHEMBL31607206 0.92 CXCR4 (0.61) CXCR4NTSR2NTSR1SORT1KISS1R
SCHEMBL34461095 0.92 CXCR4 (0.68) CXCR4NTSR2NTSR1SORT1KISS1R
SCHEMBL34461110 0.91 DPP3 (0.53) CXCR4KISS1RCAPN1CTSBDPP3
SCHEMBL34461090 0.91 DPP3 (0.59) CXCR4KISS1RDPP3C5AR1
SCHEMBL34461103 0.90 CXCR4 (0.66) CXCR4NTSR2NTSR1SORT1KISS1R
SCHEMBL34461114 0.89 DPP3 (0.55) CXCR4KISS1RDPP3C5AR1F13A1
SCHEMBL30797894 0.89 KISS1R (0.56) CXCR4NTSR2NTSR1SORT1KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098072-A1 METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS ENDEVICA BIO INC (US) 2026-04-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098072-A1 METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS MC1R, MC4R, MC5R CXCR4 2538/4885NTSR2 24/4885NTSR1 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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