Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.54 |
| ▸ | MERTK | Q12866 | 10/20 | 0.49 |
| ▸ | TYRO3 | Q06418 | 7/20 | 0.49 |
| ▸ | FLT3 | P36888 | 4/20 | 0.49 |
| ▸ | GAS6 | Q14393 | 2/20 | 0.49 |
| ▸ | AXL | P30530 | 4/20 | 0.46 |
| ▸ | CDK4 | P11802 | 4/20 | 0.44 |
| ▸ | CCND1 | P24385 | 4/20 | 0.44 |
| ▸ | CCND2 | P30279 | 2/20 | 0.44 |
| ▸ | CCND3 | P30281 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34462155 | 0.93 | AXL (0.53) | TLR7MERTKTYRO3AXLCDK4 | |
| SCHEMBL34462340 | 0.89 | AXL (0.47) | TLR7MERTKTYRO3FLT3GAS6 | |
| SCHEMBL34462145 | 0.89 | AXL (0.47) | TLR7MERTKTYRO3FLT3AXL | |
| SCHEMBL34462209 | 0.89 | AXL (0.47) | TLR7MERTKTYRO3FLT3GAS6 | |
| SCHEMBL34462250 | 0.88 | MERTK (0.48) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL34462210 | 0.88 | PRKDC (0.49) | TLR7MERTKTYRO3FLT3GAS6 | |
| SCHEMBL34462348 | 0.87 | CCND3 (0.52) | TLR7MERTKTYRO3FLT3GAS6 | |
| SCHEMBL34462179 | 0.84 | MERTK (0.43) | MERTKTYRO3AXLCDK4CCND1 | |
| SCHEMBL34462296 | 0.84 | AXL (0.42) | TLR7MERTKTYRO3FLT3GAS6 | |
| SCHEMBL34462234 | 0.83 | PRKDC (0.49) | MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | claimed |
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | disclosed |