Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 16/20 | 0.48 |
| ▸ | AXL | P30530 | 9/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 11/20 | 0.45 |
| ▸ | FLT3 | P36888 | 6/20 | 0.45 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.43 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.43 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34462340 | 0.89 | AXL (0.47) | MERTKAXLTYRO3FLT3GAS6 | |
| SCHEMBL34462209 | 0.89 | AXL (0.47) | MERTKAXLTYRO3FLT3GAS6 | |
| SCHEMBL34462145 | 0.89 | AXL (0.47) | MERTKAXLTYRO3FLT3ADORA2A | |
| SCHEMBL34462210 | 0.88 | PRKDC (0.49) | MERTKAXLTYRO3FLT3GAS6 | |
| SCHEMBL34462231 | 0.88 | TLR7 (0.54) | MERTKAXLTYRO3FLT3GAS6 | |
| SCHEMBL34462155 | 0.85 | AXL (0.53) | MERTKAXLTYRO3NUAK1 | |
| SCHEMBL34462179 | 0.84 | MERTK (0.43) | MERTKAXLTYRO3ADORA2AADORA1 | |
| SCHEMBL34462218 | 0.84 | ADORA2A (0.54) | MERTKTYRO3FLT3GAS6ADORA2A | |
| SCHEMBL34462154 | 0.83 | MERTK (0.47) | MERTKAXLTYRO3FLT3GAS6 | |
| SCHEMBL34462234 | 0.83 | PRKDC (0.49) | MERTKADORA2AADORA1PRKDCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | claimed |
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | disclosed |