Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 7/20 | 0.47 |
| ▸ | MERTK | Q12866 | 16/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 10/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 4/20 | 0.41 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.41 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.41 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34462209 | 0.93 | AXL (0.47) | AXLMERTKTYRO3TLR7FLT3 | |
| SCHEMBL34462145 | 0.91 | AXL (0.47) | AXLMERTKTYRO3TLR7FLT3 | |
| SCHEMBL34462210 | 0.89 | PRKDC (0.49) | AXLMERTKTYRO3TLR7FLT3 | |
| SCHEMBL34462250 | 0.89 | MERTK (0.48) | AXLMERTKTYRO3FLT3NUAK1 | |
| SCHEMBL34462231 | 0.89 | TLR7 (0.54) | AXLMERTKTYRO3TLR7FLT3 | |
| SCHEMBL34462179 | 0.88 | MERTK (0.43) | AXLMERTKTYRO3 | |
| SCHEMBL34462155 | 0.86 | AXL (0.53) | AXLMERTKTYRO3TLR7NUAK1 | |
| SCHEMBL34462205 | 0.85 | AXL (0.43) | AXLMERTKTYRO3TLR7FLT3 | |
| SCHEMBL34462234 | 0.84 | PRKDC (0.49) | MERTK | |
| SCHEMBL34462228 | 0.83 | CYP1A2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | disclosed |