Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.37 |
| ▸ | MERTK | Q12866 | 2/20 | 0.37 |
| ▸ | GAS6 | Q14393 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | USP1 | O94782 | 5/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34462265 | 0.94 | USP2 (0.39) | FLT3TYRO3MERTKGAS6TLR7 | |
| SCHEMBL34462158 | 0.90 | TLR7 (0.36) | FLT3TYRO3MERTKTLR7ADORA2A | |
| SCHEMBL34462260 | 0.89 | DRD3 (0.37) | FLT3TYRO3MERTKTLR7AXL | |
| SCHEMBL34462167 | 0.89 | ADORA2A (0.39) | MERTKTLR7ADORA2AADORA1ALDH1A1 | |
| SCHEMBL34462171 | 0.86 | TLR7 (0.37) | FLT3TYRO3MERTKGAS6TLR7 | |
| SCHEMBL34462275 | 0.85 | TLR7 (0.45) | TLR7USP1P2RX3 | |
| SCHEMBL34462256 | 0.85 | ADORA2A (0.40) | FLT3TYRO3MERTKGAS6TLR7 | |
| SCHEMBL34462238 | 0.83 | CYP1A2 (0.39) | TLR7ADORA2AADORA1USP2ALDH1A1 | |
| SCHEMBL34462235 | 0.83 | USP2 (0.39) | TLR7USP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL34462173 | 0.82 | ALDH1A1 (0.44) | TLR7ADORA2AADORA1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | claimed |
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | disclosed |