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Sugi Predict / Compounds / SCHEMBL34462275

SCHEMBL34462275

SCHEMBL34462275

CCOc1ncc2c(n1)n(Cc1ccc(C(F)(F)F)cc1)c(=O)n2CCCN1CC2CC1CN2C

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ TLR7 Q9NYK1 17/20 0.45
▸ P2RX3 P56373 1/20 0.34
▸ USP1 O94782 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34462317 0.90 TLR7 (0.45) TLR7USP1
SCHEMBL34462174 0.89 TLR7 (0.45) TLR7
SCHEMBL34462163 0.89 TLR7 (0.45) TLR7
SCHEMBL34462265 0.87 USP2 (0.39) TLR7P2RX3USP1
SCHEMBL34462159 0.86 TLR7 (0.41) TLR7USP1
SCHEMBL34462232 0.85 FLT3 (0.37) TLR7P2RX3USP1
SCHEMBL34462173 0.76 ALDH1A1 (0.44) TLR7
SCHEMBL34462238 0.76 CYP1A2 (0.39) TLR7
SCHEMBL34462235 0.75 USP2 (0.39) TLR7
SCHEMBL34462167 0.75 ADORA2A (0.39) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724442-A1 AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF Council of Scientific and Industrial Research (IN) 2026-04-15 — — EP claimed
EP-4724442-A1 AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF Council of Scientific and Industrial Research (IN) 2026-04-15 — — EP disclosed
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