Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 9/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 9/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34462302 | 0.90 | AGTR1 (0.51) | AGTR1AGTR2MAPK8ALDH1A1SMN1; SMN2 | |
| SCHEMBL34462329 | 0.89 | KDM4E (0.52) | AGTR1AGTR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL34462354 | 0.89 | AGTR1 (0.47) | AGTR1AGTR2MAPK8KDM4EALDH1A1 | |
| SCHEMBL34462342 | 0.87 | AGTR1 (0.45) | AGTR1AGTR2MAPK8KDM4EALDH1A1 | |
| SCHEMBL34462359 | 0.84 | AGTR1 (0.43) | AGTR1AGTR2MAPK8KDM4EALDH1A1 | |
| SCHEMBL34462311 | 0.83 | AGTR1 (0.43) | AGTR1AGTR2MAPK8 | |
| SCHEMBL34462321 | 0.80 | KDM4E (0.54) | AGTR1AGTR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL34462293 | 0.74 | TYRO3 (0.53) | KDM4EASPHRIOX2KDM8 | |
| SCHEMBL27870476 | 0.72 | ALDH1A1 (0.49) | KDM4EALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL4765629 | 0.71 | NPC1 (0.63) | MAPK8KDM4EALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | disclosed |