SCHEMBL34463397

SCHEMBL34463397

CN(C)c1ccc(-c2ccc(C=C(C#N)C#N)c3nsnc23)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 10/20 0.48
▸ ALDH1A1 P00352 8/20 0.48
▸ MEN1 O00255 7/20 0.48
▸ KMT2A Q03164 7/20 0.48
▸ APP P05067 7/20 0.45
▸ LMNA P02545 4/20 0.42
▸ RAB9A P51151 4/20 0.42
▸ KDM4E B2RXH2 3/20 0.42
▸ SMN1; SMN2 Q16637 3/20 0.42
▸ NPC1 O15118 3/20 0.42
▸ L3MBTL1 Q9Y468 3/20 0.42
▸ POLB P06746 2/20 0.42
▸ NPSR1 Q6W5P4 2/20 0.42
▸ HSP90AA1 P07900 1/20 0.42
▸ THRB P10828 1/20 0.42
▸ HTT P42858 1/20 0.42
▸ PLEC Q15149 1/20 0.38
▸ SNCA P37840 1/20 0.36
▸ TNNI3 P19429 1/20 0.34
▸ TNNT2 P45379 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14634491 0.87 MAPT (0.39) MAPTALDH1A1MEN1KMT2AAPP
SCHEMBL14634382 0.85 MAPT (0.38) MAPTALDH1A1MEN1KMT2AAPP
SCHEMBL711589 0.79 MAPT (0.45) MAPTALDH1A1MEN1KMT2AAPP
SCHEMBL14634376 0.77 MAPT (0.36) MAPTALDH1A1MEN1KMT2AAPP
Diphenylamine SCHEMBL14634383 0.77 TRPA1 (0.35) MAPTALDH1A1MEN1KMT2AAPP
SCHEMBL22102776 0.74 MEN1 (0.44) MAPTALDH1A1MEN1KMT2AAPP
SCHEMBL14634373 0.74 MAPT (0.39) MAPTALDH1A1MEN1KMT2AAPP
SCHEMBL29090586 0.74 MAPT (0.35) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL31314381 0.74 MAPT (0.35) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL29102222 0.73 ALDH1A1 (0.41) MAPTALDH1A1MEN1KMT2AAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103820-A1 METHOD FOR PREPARING FULLERENE SINGLE-CRYSTAL FILMS AND USES FIELD OF TECHNOLOGY ZHEJIANG UNIVERSITY (CN) 2026-04-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103820-A1 METHOD FOR PREPARING FULLERENE SINGLE-CRYSTAL FILMS AND USES FIELD OF TECHNOLOGY CCNE2, MDM4, FSCN1 MAPT 946/4885ALDH1A1 4607/4885MEN1 1856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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