SCHEMBL3446357

SCHEMBL3446357

C=Cc1cccc(OCCCCN(C(C)CC)C(C)CC)c1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TLR4 O00206 1/20 0.40
TLR2 O60603 1/20 0.40
TSHR P16473 2/20 0.39
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
FURIN P09958 1/20 0.36
MAOB P27338 3/20 0.36
MAOA P21397 2/20 0.35
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34
CHRNA7 P36544 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3446671 0.99 KDM4E (0.39) KDM4EALDH1A1LMNASMN1; SMN2TLR4
SCHEMBL3446076 0.99 KDM4E (0.39) KDM4EALDH1A1LMNASMN1; SMN2TLR4
SCHEMBL3444785 0.96 TLR4 (0.40) KDM4EALDH1A1LMNASMN1; SMN2TLR4
SCHEMBL3444839 0.88 CHRNB2 (0.43) KDM4EALDH1A1LMNASMN1; SMN2TLR4
SCHEMBL3445339 0.87 CHRNB2 (0.42) KDM4EALDH1A1LMNASMN1; SMN2TLR4
SCHEMBL4359013 0.87 CHRNB2 (0.42) KDM4EALDH1A1LMNASMN1; SMN2TLR4
SCHEMBL3444150 0.84 CHRNB2 (0.43) KDM4EALDH1A1LMNASMN1; SMN2TLR4
SCHEMBL3444410 0.84 CHRNB2 (0.49) KDM4EALDH1A1LMNASMN1; SMN2MAPT
SCHEMBL3446644 0.84 TLR4 (0.41) KDM4EALDH1A1LMNASMN1; SMN2TLR4
SCHEMBL3446522 0.83 CHRNB2 (0.48) KDM4EALDH1A1MAOBMAOACHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816475-B2 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION (JP) 2010-10-19 US disclosed
EP-1829857-B1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORP (JP) 2009-11-04 EP disclosed
US-20070213490-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION 2007-09-13 US disclosed
EP-1829857-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof Tosoh Corporation (JP) 2007-09-05 EP disclosed