SCHEMBL3446644

SCHEMBL3446644

C=Cc1cccc(OCCCN(CCC)C(C)CC)c1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 1/20 0.41
TLR2 O60603 1/20 0.41
KDM4E B2RXH2 4/20 0.39
TSHR P16473 2/20 0.39
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
FURIN P09958 1/20 0.35
BCHE P06276 2/20 0.35
ACHE P22303 2/20 0.35
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
LMNA P02545 1/20 0.34
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3445058 0.91 TLR4 (0.42) TLR4TLR2KDM4ETSHRMAOA
SCHEMBL3444785 0.87 TLR4 (0.40) TLR4TLR2KDM4ETSHRMAOA
SCHEMBL3444178 0.86 TLR4 (0.45) TLR4TLR2KDM4ETSHRMAOA
SCHEMBL4543255 0.85 MAOA (0.42) TLR4TLR2KDM4ETSHRMAOA
SCHEMBL3444993 0.84 CHRNB2 (0.48) KDM4EMAOAMAOBBCHEACHE
SCHEMBL3446357 0.84 KDM4E (0.40) TLR4TLR2KDM4ETSHRMAOA
SCHEMBL3445719 0.83 BCHE (0.48) TLR4TLR2KDM4ETSHRMAOA
SCHEMBL3446076 0.82 KDM4E (0.39) TLR4TLR2KDM4ETSHRMAOA
SCHEMBL3446671 0.82 KDM4E (0.39) TLR4TLR2KDM4ETSHRMAOA
SCHEMBL3446155 0.81 KDM4E (0.43) TLR4TLR2KDM4ETSHRMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816475-B2 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION (JP) 2010-10-19 US disclosed
EP-1829857-B1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORP (JP) 2009-11-04 EP disclosed
US-20070213490-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION 2007-09-13 US disclosed
EP-1829857-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof Tosoh Corporation (JP) 2007-09-05 EP disclosed