SCHEMBL3446377

SCHEMBL3446377

C=Cc1ccccc1OCCCCCN(CCCC)CCCC

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
HTR1B P28222 2/20 0.52
HTR1D P28221 1/20 0.47
BCHE P06276 4/20 0.44
ACHE P22303 3/20 0.44
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3445462 1.00 ALDH1A1 (0.52) ALDH1A1HTR1BHTR1DBCHEACHE
SCHEMBL3445043 0.98 HTR1B (0.54) ALDH1A1HTR1BHTR1DBCHEACHE
SCHEMBL3444498 0.94 ALDH1A1 (0.52) ALDH1A1HTR1BBCHEACHE
SCHEMBL3446379 0.94 ALDH1A1 (0.52) ALDH1A1HTR1BBCHEACHE
SCHEMBL3444957 0.94 HTR1B (0.55) ALDH1A1HTR1BHTR1DBCHE
SCHEMBL3446798 0.93 ALDH1A1 (0.50) ALDH1A1HTR1BHTR1DBCHEACHE
SCHEMBL3445323 0.91 HTR1B (0.52) ALDH1A1HTR1BHTR1DBCHEACHE
SCHEMBL3445440 0.90 ALDH1A1 (0.66) ALDH1A1HTR1BHTR1DBCHEACHE
SCHEMBL3445531 0.90 ALDH1A1 (0.66) ALDH1A1HTR1BHTR1DBCHEACHE
SCHEMBL3445823 0.88 HTR1B (0.48) ALDH1A1HTR1BHTR1DBCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816475-B2 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION (JP) 2010-10-19 US disclosed
EP-1829857-B1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORP (JP) 2009-11-04 EP disclosed
US-20070213490-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION 2007-09-13 US disclosed
EP-1829857-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof Tosoh Corporation (JP) 2007-09-05 EP disclosed