SCHEMBL3445440

SCHEMBL3445440

C=Cc1ccccc1OCCCCCCN(CC)CC

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.66
BCHE P06276 2/20 0.51
ACHE P22303 2/20 0.51
HTR1D P28221 1/20 0.45
HTR1B P28222 1/20 0.45
DRD2 P14416 1/20 0.44
DRD1 P21728 1/20 0.44
DRD3 P35462 1/20 0.44
CHRM2 P08172 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3445531 1.00 ALDH1A1 (0.66) ALDH1A1BCHEACHEHTR1DHTR1B
SCHEMBL3445434 0.98 ALDH1A1 (0.63) ALDH1A1BCHEACHEHTR1DHTR1B
SCHEMBL3445006 0.94 ALDH1A1 (0.56) ALDH1A1BCHEACHEHTR1DHTR1B
SCHEMBL3444498 0.90 ALDH1A1 (0.52) ALDH1A1BCHEACHEHTR1B
SCHEMBL3446379 0.90 ALDH1A1 (0.52) ALDH1A1BCHEACHEHTR1B
SCHEMBL3445462 0.90 ALDH1A1 (0.52) ALDH1A1BCHEACHEHTR1DHTR1B
SCHEMBL3446377 0.90 ALDH1A1 (0.52) ALDH1A1BCHEACHEHTR1DHTR1B
SCHEMBL3445043 0.88 HTR1B (0.54) ALDH1A1BCHEACHEHTR1DHTR1B
SCHEMBL3446798 0.88 ALDH1A1 (0.50) ALDH1A1BCHEACHEHTR1DHTR1B
SCHEMBL3446080 0.84 HTR1B (0.56) ALDH1A1HTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816475-B2 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION (JP) 2010-10-19 US disclosed
EP-1829857-B1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORP (JP) 2009-11-04 EP disclosed
US-20070213490-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION 2007-09-13 US disclosed
EP-1829857-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof Tosoh Corporation (JP) 2007-09-05 EP disclosed