Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | GRAMD1A | Q96CP6 | 6/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21997600 | 1.00 | STAT3 (0.53) | STAT3MAP1LC3BCRBNDDB1GRAMD1A | |
| SCHEMBL30936855 | 0.97 | STAT3 (0.55) | STAT3MAP1LC3BCRBNDDB1GRAMD1A | |
| SCHEMBL30936833 | 0.93 | STAT3 (0.52) | STAT3MAP1LC3BCRBNDDB1GRAMD1A | |
| SCHEMBL23696490 | 0.89 | MAP1LC3B (0.54) | STAT3MAP1LC3BCRBNDDB1BRD4 | |
| SCHEMBL21997194 | 0.88 | STAT3 (0.56) | STAT3MAP1LC3BCRBNDDB1GRAMD1A | |
| SCHEMBL21997854 | 0.87 | CRBN (0.55) | CRBNDDB1 | |
| SCHEMBL30042075 | 0.87 | MAP1LC3B (0.53) | STAT3MAP1LC3BCRBNDDB1GRAMD1A | |
| SCHEMBL28909808 | 0.87 | MAP1LC3B (0.53) | STAT3MAP1LC3BCRBNDDB1GRAMD1A | |
| SCHEMBL23066044 | 0.87 | CRBN (0.51) | MAP1LC3BCRBNBRD4 | |
| SCHEMBL25539454 | 0.86 | MAP1LC3B (0.59) | STAT3MAP1LC3BCRBNDDB1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3886904-B1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-04-22 | — | — | EP | disclosed |