Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.54 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187848 | 1.00 | CASP3 (0.65) | CASP3CA1CA2CA4CA9 | |
| SCHEMBL5573576 | 0.90 | TDP1 (0.66) | CASP3CA1CA2CA4CA9 | |
| SCHEMBL3792244 | 0.87 | TDP1 (0.77) | CYP1B1TDP1L3MBTL1GSK3B | |
| SCHEMBL10488503 | 0.86 | CASP3 (0.65) | CASP3CA1CA2CA4CA9 | |
| SCHEMBL1429821 | 0.86 | CASP3 (0.65) | CASP3CA1CA2CA4CA9 | |
| SCHEMBL1142116 | 0.85 | CASP3 (0.86) | CASP3CA1CA2CA4CA9 | |
| SCHEMBL29724090 | 0.85 | CASP3 (0.86) | CASP3CA1CA2CA4CA9 | |
| SCHEMBL18074272 | 0.84 | CASP3 (0.67) | CASP3CA1CA2CA4CA9 | |
| SCHEMBL10586404 | 0.83 | ALDH1A1 (0.68) | CASP3CA1CA2CA4CA9 | |
| SCHEMBL7954280 | 0.82 | CASP3 (0.65) | CASP3CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3886904-B1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-04-22 | — | — | EP | disclosed |