SCHEMBL34464867

SCHEMBL34464867

CN1CCN(C(=O)c2ccc(Nc3nccc(-c4ccc(C(=O)O)cc4)n3)cc2F)CC1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CAMK2D Q13557 5/20 0.53
▸ GSK3B P49841 2/20 0.52
▸ MAPK8 P45983 1/20 0.52
▸ PIK3CG P48736 1/20 0.52
▸ CAMKK2 Q96RR4 1/20 0.52
▸ JAK2 O60674 3/20 0.50
▸ SYK P43405 7/20 0.49
▸ CDK2 P24941 2/20 0.49
▸ CDK1 P06493 1/20 0.49
▸ CCNA2 P20248 1/20 0.49
▸ CCNA1 P78396 1/20 0.49
▸ JAK3 P52333 2/20 0.49
▸ PIM1 P11309 1/20 0.48
▸ CDK4 P11802 1/20 0.48
▸ CCND3 P30281 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34464796 0.91 SYK (0.50) CAMK2DJAK2SYKCDK2CDK1
SCHEMBL34464820 0.91 JAK2 (0.54) CAMK2DJAK2SYKCDK2CDK1
SCHEMBL34464794 0.89 JAK2 (0.56) CAMK2DGSK3BMAPK8PIK3CGCAMKK2
Formic Acid SCHEMBL34464810 0.88 JAK2 (0.51) CAMK2DJAK2SYKCDK2CDK1
SCHEMBL34464824 0.85 CAMK2D (0.48) CAMK2DGSK3BMAPK8PIK3CGCAMKK2
SCHEMBL34464826 0.83 ABL1 (0.61) CAMK2DGSK3BMAPK8PIK3CGCAMKK2
SCHEMBL34464767 0.82 CAMK2D (0.55) CAMK2DGSK3BMAPK8PIK3CGCAMKK2
SCHEMBL34464745 0.81 JAK2 (0.56) CAMK2DMAPK8JAK2SYKCDK2
SCHEMBL34464802 0.81 JAK2 (0.53) CAMK2DJAK2CDK2CDK1JAK3
SCHEMBL34464746 0.80 JAK2 (0.67) CAMK2DMAPK8JAK2SYKCDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109690-A1 HDAC6 INHIBITORS AND METHOD OF THEIR USE BAERENKRAFT THERAPEUTICS LLC (US) 2026-04-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109690-A1 HDAC6 INHIBITORS AND METHOD OF THEIR USE HDAC6, HDAC3, HDAC1 CAMK2D 378/4885GSK3B 285/4885MAPK8 2486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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