SCHEMBL34465060

SCHEMBL34465060

C[C@H]1c2c3cc(Br)c(Cl)c(F)c3nn2[C@H](CCO)CN1C(=O)OC(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 1/20 0.31
▸ USP30 Q70CQ3 1/20 0.30
▸ SSTR4 P31391 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34465061 1.00 CNR1 (0.31) CNR1USP30SSTR4
SCHEMBL35212429 0.91 PARP1 (0.33) USP30
SCHEMBL34466687 0.91 PARP1 (0.33) USP30
SCHEMBL34466688 0.91 PARP1 (0.33) USP30
SCHEMBL34465081 0.91 PARP1 (0.33) USP30
SCHEMBL34465124 0.89 USP30 (0.33) CNR1USP30
SCHEMBL34465074 0.89 USP30 (0.33) CNR1USP30
SCHEMBL34465158 0.89 USP30 (0.30) USP30
SCHEMBL35212331 0.88 USP30 (0.32) USP30
SCHEMBL34465127 0.88 USP30 (0.32) USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108510-A1 PYRAZOLYL INDAZOLE CGAS INHIBITORS AND USES THEREOF VENTUS THERAPEUTICS U.S., INC. (US) 2026-04-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108510-A1 PYRAZOLYL INDAZOLE CGAS INHIBITORS AND USES THEREOF CGAS, GBA3, CYP11B2 CNR1 703/4885USP30 3974/4885SSTR4 801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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