SCHEMBL34466004

SCHEMBL34466004

COC(COc1cc2c3n(nc2c(F)c1Cl)CCN(C(=O)OC(C)(C)C)C3C)OC

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ SCN9A Q15858 1/20 0.31
▸ ALOX5AP P20292 1/20 0.30
▸ FEN1 P39748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34465705 1.00 SCN9A (0.31) SCN9AALOX5APFEN1
SCHEMBL35211102 0.88 TLR9 (0.35) —
SCHEMBL34465680 0.86 — —
SCHEMBL34466128 0.82 GRM5 (0.33) —
SCHEMBL34465741 0.82 UCHL1 (0.33) —
SCHEMBL34466888 0.82 UCHL1 (0.33) —
SCHEMBL34466163 0.82 GRM5 (0.33) —
SCHEMBL35211325 0.79 SUV39H2 (0.37) —
SCHEMBL34466640 0.79 SUV39H2 (0.37) —
SCHEMBL35210758 0.79 SUV39H2 (0.37) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109704-A1 5-MEMBERED HETEROARYL INDAZOLE CGAS INHIBITORS AND USES THEREOF VENTUS THERAPEUTICS U.S., INC. (US) 2026-04-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109704-A1 5-MEMBERED HETEROARYL INDAZOLE CGAS INHIBITORS AND USES THEREOF CGAS, GBA3, CYP11B2 SCN9A 2685/4885ALOX5AP 4128/4885FEN1 490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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