Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.31 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34465741 | 0.91 | UCHL1 (0.33) | GRM5NR1H2ALDH1A1UCHL1MAP4K4 | |
| SCHEMBL34466888 | 0.91 | UCHL1 (0.33) | GRM5NR1H2ALDH1A1UCHL1MAP4K4 | |
| SCHEMBL35210758 | 0.88 | SUV39H2 (0.37) | GRM5ALDH1A1MAP4K4MEN1KMT2A | |
| SCHEMBL35211325 | 0.88 | SUV39H2 (0.37) | GRM5ALDH1A1MAP4K4MEN1KMT2A | |
| SCHEMBL34466640 | 0.88 | SUV39H2 (0.37) | GRM5ALDH1A1MAP4K4MEN1KMT2A | |
| SCHEMBL26130129 | 0.84 | GRM5 (0.36) | GRM5ALDH1A1MAP4K4OPRK1MEN1 | |
| SCHEMBL34466128 | 0.82 | GRM5 (0.33) | GRM5NR1H2ALDH1A1MAP4K4USP30 | |
| SCHEMBL34466163 | 0.82 | GRM5 (0.33) | GRM5NR1H2ALDH1A1MAP4K4USP30 | |
| SCHEMBL34466671 | 0.82 | ALDH1A1 (0.34) | ALDH1A1OPRK1MEN1LMNAMAPT | |
| SCHEMBL35211102 | 0.81 | TLR9 (0.35) | GRM5ALDH1A1USP30LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260108509-A1 | 6-MEMBERED HETEROARYL INDAZOLE CGAS INHIBITORS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2026-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260108509-A1 | 6-MEMBERED HETEROARYL INDAZOLE CGAS INHIBITORS AND USES THEREOF | CGAS, GBA3, GBA1 | GRM5 4003/4885NR1H2 614/4885ALDH1A1 1475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.