SCHEMBL34466565

SCHEMBL34466565

O=C1CCC(N2Cc3cc(OCCN4CCN(c5ccc(Nc6ccc(N7CCNCC7)cc6)cc5Cl)CC4)ccc3C2=O)C(=O)N1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ WIZ O95785 3/20 0.52
▸ CRBN Q96SW2 11/20 0.46
▸ IKZF3 Q9UKT9 5/20 0.46
▸ GSPT1 P15170 1/20 0.46
▸ DDB1 Q16531 1/20 0.46
▸ IKZF2 Q9UKS7 6/20 0.44
▸ ESR1 P03372 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34466813 0.87 CRBN (0.47) WIZCRBNIKZF3GSPT1DDB1
SCHEMBL34466550 0.87 CRBN (0.47) WIZCRBNIKZF3GSPT1DDB1
SCHEMBL34466615 0.86 CRBN (0.52) CRBNIKZF3GSPT1DDB1IKZF2
SCHEMBL34465543 0.84 CRBN (0.50) WIZCRBNIKZF3GSPT1DDB1
SCHEMBL34465544 0.84 CRBN (0.50) WIZCRBNIKZF3GSPT1DDB1
SCHEMBL34465844 0.83 IKZF2 (0.48) WIZCRBNIKZF3GSPT1DDB1
SCHEMBL34465823 0.83 WIZ (0.49) WIZCRBNIKZF3IKZF2ESR1
SCHEMBL34465924 0.83 WIZ (0.43) WIZCRBNIKZF3GSPT1DDB1
SCHEMBL34465708 0.83 CRBN (0.47) WIZCRBNIKZF3GSPT1DDB1
SCHEMBL34466876 0.83 IKZF2 (0.47) WIZCRBNIKZF3GSPT1DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109702-A1 NOVEL GSPT PROTEIN DEGRADER AND APPLICATION THEREOF GENOSCO INC (US) 2026-04-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109702-A1 NOVEL GSPT PROTEIN DEGRADER AND APPLICATION THEREOF CRBN, PSMB3, PSMB1 WIZ 1242/4885CRBN 1/4885IKZF3 1564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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