Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34468572 | 0.89 | ALDH1A1 (0.61) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL34468532 | 0.77 | KDM4E (0.58) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL10406531 | 0.75 | KMT2A (0.75) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL11356974 | 0.75 | ALDH1A1 (0.75) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL18542006 | 0.74 | MAPK1 (1.00) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL34468553 | 0.74 | KDM4E (0.67) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL11490028 | 0.73 | ALDH1A1 (0.77) | ALDH1A1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL10612470 | 0.72 | MAPK1 (0.71) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL8289398 | 0.72 | ALDH1A1 (0.61) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL1622930 | 0.71 | MAPK1 (0.78) | ALDH1A1GAAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | TEXAS CROP SCIENCE INC (US) | 2026-04-30 | — | — | US | claimed |
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | TEXAS CROP SCIENCE INC (US) | 2026-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | SRR, APEH, OSR1 | ALDH1A1 2701/4885GAA 1257/4885KMT2A 3764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.