SCHEMBL34469080

SCHEMBL34469080

CC1Cn2cncc2CN1C(=O)OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 7/20 0.38
▸ MAP4K4 O95819 1/20 0.37
▸ SPR P35270 5/20 0.36
▸ HDAC1 Q13547 1/20 0.36
▸ SETD7 Q8WTS6 1/20 0.35
▸ PTPN1 P18031 1/20 0.35
▸ ELANE P08246 1/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17596207 0.76 MAP4K4 (0.37) GPR119MAP4K4SPRHDAC1SETD7
SCHEMBL19784976 0.76 GPR119 (0.38) GPR119MAP4K4SPRHDAC1SETD7
SCHEMBL17596209 0.76 MAP4K4 (0.37) GPR119MAP4K4SPRHDAC1SETD7
SCHEMBL17926262 0.76 MAP4K4 (0.39) GPR119MAP4K4SPRHDAC1SETD7
SCHEMBL17936822 0.76 MAP4K4 (0.39) GPR119MAP4K4SPRHDAC1SETD7
SCHEMBL17936828 0.76 MAP4K4 (0.39) GPR119MAP4K4SPRHDAC1SETD7
SCHEMBL5765341 0.74 NR1H2 (0.49) GPR119
SCHEMBL21058315 0.74 GPR119 (0.38) GPR119MAP4K4SPRHDAC1SETD7
SCHEMBL19632326 0.74 GPR119 (0.38) GPR119MAP4K4SPRHDAC1SETD7
SCHEMBL34469336 0.73 GPR119 (0.38) GPR119MAP4K4HDAC1SETD7MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115174-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT INC (US) 2026-04-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115174-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF PDE6D, PDE6H, ADRA1D GPR119 904/4885MAP4K4 2227/4885SPR 3189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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