SCHEMBL34469258

SCHEMBL34469258

Cn1nc(C(F)(F)F)c2c1CN(C=O)CC2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 2/20 0.40
▸ DPP8 Q6V1X1 2/20 0.40
▸ DPP7 Q9UHL4 2/20 0.40
▸ DPP9 Q86TI2 1/20 0.40
▸ GRIA2 P42262 4/20 0.38
▸ LMNA P02545 3/20 0.37
▸ TSHR P16473 1/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.34
▸ POLQ O75417 1/20 0.34
▸ CYP2C9 P11712 2/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ PDE10A Q9Y233 1/20 0.33
▸ POLB P06746 2/20 0.33
▸ CYP1A2 P05177 2/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ KCNJ2 P63252 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15730164 0.80 GRIA2 (0.49) DPP4DPP8DPP7DPP9GRIA2
SCHEMBL14970356 0.75 DPP4 (0.51) DPP4DPP8DPP7DPP9LMNA
SCHEMBL6369616 0.75 DPP4 (0.41) DPP4DPP8DPP7DPP9GRIA2
SCHEMBL19722755 0.74 DPP4 (0.50) DPP4DPP8DPP7DPP9GRIA2
SCHEMBL19097281 0.72 KCNK3 (0.43) GRIA2LMNATSHRNPSR1POLQ
SCHEMBL15730331 0.71 LMNA (0.51) GRIA2LMNATSHRNPSR1GAA
SCHEMBL14401055 0.71 LMNA (0.55) GRIA2LMNATSHRNPSR1GAA
SCHEMBL15730234 0.71 LMNA (0.37) DPP4DPP8DPP7DPP9GRIA2
SCHEMBL15730073 0.70 DPP4 (0.47) DPP4DPP8DPP7DPP9LMNA
SCHEMBL15730382 0.70 GRIA2 (0.41) DPP4DPP8DPP7DPP9GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115174-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT INC (US) 2026-04-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115174-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF PDE6D, PDE6H, ADRA1D DPP4 1747/4885DPP8 2960/4885DPP7 2648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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