SCHEMBL344707

SCHEMBL344707

C=C(C)C(=O)OC(C)(CO)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TSHR P16473 3/20 0.35
THRB P10828 1/20 0.33
GAA P10253 1/20 0.33
ELANE P08246 1/20 0.32
TET2 Q6N021 1/20 0.31
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PPARG P37231 1/20 0.30
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL543869 0.82 TSHR (0.40) ALDH1A1TSHRTHRBGAAELANE
SCHEMBL344458 0.81 TSHR (0.41) ALDH1A1TSHRTHRBGAAELANE
SCHEMBL8377560 0.81 ALDH1A1 (0.45) ALDH1A1TSHRTHRBGAA
SCHEMBL963351 0.78 GAA (0.32) GAA
SCHEMBL11604329 0.78 TSHR (0.43) ALDH1A1TSHRTHRBGAAELANE
SCHEMBL7583432 0.77 ALDH1A1 (0.42) ALDH1A1TSHRTHRBGAATDP1
SCHEMBL1371760 0.77 ALDH1A1 (0.42) ALDH1A1TSHRTHRBGAATDP1
SCHEMBL1355618 0.75 ALDH1A1 (0.41) ALDH1A1TSHRTHRBGAA
SCHEMBL10477043 0.74 ALDH1A1 (0.44) ALDH1A1TSHRTHRBTDP1
SCHEMBL2608062 0.74 ALDH1A1 (0.44) ALDH1A1TSHRTHRBELANETET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104323976-B Preparation method of composition with skin tightening effect 珀莱雅化妆品股份有限公司 2017-01-11 CN claimed
CN-104323976-A Preparation method of composition with skin tightening effect PROYA COSMETICS CO LTD 2015-02-04 CN claimed
EP-2999521-B1 SYNERGISTIC PHOTOPROTECTIVE COMPOSITIONS EDGEWELL PERSONAL CARE BRANDS LLC (US) 2019-01-09 EP disclosed
CN-104323976-B Preparation method of composition with skin tightening effect 珀莱雅化妆品股份有限公司 2017-01-11 CN disclosed
CN-104323976-A Preparation method of composition with skin tightening effect PROYA COSMETICS CO LTD 2015-02-04 CN disclosed
US-20120014888-A1 Matte Skin Finish Compositions AMCOL INTERNATIONAL CORPORATION (US) 2012-01-19 US disclosed
WO-2010088185-A2 MATTE SKIN FINISH COMPOSITIONS AMCOL INTERNATIONAL CORPORATION (US) 2010-08-05 WO disclosed