Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643953 | 0.82 | ALDH1A1 (0.42) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL344707 | 0.81 | ALDH1A1 (0.38) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL543869 | 0.79 | TSHR (0.40) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL2101100 | 0.79 | TSHR (0.45) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL10937523 | 0.79 | TSHR (0.45) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL7940544 | 0.79 | TSHR (0.45) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL9241281 | 0.77 | TSHR (0.44) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL7163782 | 0.76 | TSHR (0.40) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL942089 | 0.76 | TSHR (0.47) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL51592 | 0.76 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 620 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129877-A2 | PERSONAL CARE COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2024-06-20 | — | — | WO | claimed |
| CN-116983227-A | Hydroxy pinacolone retinoic acid ester composition and application thereof in skin care products | 海南中和美业科技有限公司 | 2023-11-03 | — | — | CN | claimed |
| US-11771631-B2 | Cosmetic composition comprising a specific filler combination and a film-forming polymer to increase long-lasting effects | L'OREAL (FR) | 2023-10-03 | — | — | US | claimed |
| US-20230060807-A1 | ANTIPERSPIRANT FORMULATIONS COMPRISING HEMISQUALANE | EUAGORE, LLC | 2023-03-02 | — | — | US | claimed |
| US-11554086-B2 | Cosmetic composition comprising glycolic acid and methods of use | L'OREAL (FR) | 2023-01-17 | — | — | US | claimed |
| US-11179305-B2 | Topical compositions | MARY KAY INC. (US) | 2021-11-23 | — | — | US | claimed |
| US-11147722-B2 | Absorbent article with a multifunctional acrylate skin-adhesive composition | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2021-10-19 | — | — | US | claimed |
| EP-3840721-A1 | SKIN CARE COMPOSITION | The Procter & Gamble Company (US) | 2021-06-30 | — | — | EP | claimed |
| US-20210007955-A1 | COSMETIC COMPOSITION COMPRISING A SPECIFIC FILLER COMBINATION AND A FILM-FORMING POLYMER TO INCREASE LONG-LASTING EFFECTS | L'OREAL (FR) | 2021-01-14 | — | — | US | claimed |
| US-20200297600-A1 | TOPICAL COMPOSITIONS | MARY KAY INC. (US) | 2020-09-24 | — | — | US | claimed |
| US-20090246156-A1 | ANTI-ACNE SUNSCREEN COMPOSITION | DERMADOCTOR, INC. | 2009-10-01 | — | — | US | claimed |
| EP-1811013-B1 | Foamable alcoholic composition | GOJO IND INC (US) | 2009-08-12 | — | — | EP | claimed |
| WO-2009073729-A2 | COMPOSITIONS CONTAINING BENEFIT AGENTS COMPOSITES PRE-EMULSIFIED USING COLLOIDAL CATIONIC PARTICLES | AMCOL INTERNATIONAL CORPORATION (US) | 2009-06-11 | — | — | WO | claimed |
| US-20090148392-A1 | COMPOSITIONS CONTAINING BENEFIT AGENTS PRE-EMULSIFIED USING COLLOIDAL CATIONIC PARTICLES | AMCOL INTERNATIONAL CORPORATION (US) | 2009-06-11 | — | — | US | claimed |
| US-20090022818-A1 | HIGH-FOAMING, VISCOUS CLEANSER COMPOSITION WITH A SKIN CARE AGENT | AMCOL INTERNATIONAL CORPORATION (US) | 2009-01-22 | — | — | US | claimed |
| WO-2008154107-A1 | SELF-HEALING POLYMER COMPOSITIONS | ELC MANAGEMENT LLC (US) | 2008-12-18 | — | — | WO | claimed |
| US-7455850-B2 | Two-part cosmetic product | AVON PRODUCTS. INC. (US) | 2008-11-25 | — | — | US | claimed |
| US-20060140895-A1 | Filling and swelling effect to lips, reducing appearance of fine lines and wrinkles; first topically applying an anhydrous, wax-free water absorbent polymer, then applying a wax-free, water-based composition of a water soluble or water dispersible film former onto said base coat, which swells the polymer | AVON PRODUCTS, INC. | 2006-06-29 | — | — | US | claimed |
| EP-1273284-A2 | High SPF nontacky/nongreasy UV-photoprotecting compositions comprising particulates of MMA crosspolymers | Société L'Oréal S.A. (FR) | 2003-01-08 | — | — | EP | claimed |
| US-6432389-B1 | SYNTHETIC COPOLYMER OF METHYL METHACRYLATE CROSSLINKED WITH ETHYLENE GLYCOL DIMETHACRYLATE | SOCIETE L'OREAL (FR) | 2002-08-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210007955-A1 | COSMETIC COMPOSITION COMPRISING A SPECIFIC FILLER COMBINATION AND A FILM-FORMING POLYMER TO INCREASE LONG-LASTING EFFECTS | CUTA, KRT18, PUF60 | TSHR 3249/4885THRB 4181/4885ALDH1A1 2683/4885 |
| US-20230060807-A1 | ANTIPERSPIRANT FORMULATIONS COMPRISING HEMISQUALANE | HRH2, HRH1, HMBS | TSHR 3865/4885THRB 2884/4885ALDH1A1 1117/4885 |
| US-11554086-B2 | Cosmetic composition comprising glycolic acid and methods of use | CUTA, UGCG, DGKI | TSHR 1494/4885THRB 3911/4885ALDH1A1 2910/4885 |
| US-11771631-B2 | Cosmetic composition comprising a specific filler combination and a film-forming polymer to increase long-lasting effects | CUTA, KRT18, PUF60 | TSHR 3249/4885THRB 4181/4885ALDH1A1 2683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.