SCHEMBL34470985

SCHEMBL34470985

CC(=O)N1CCc2[nH]nc(C3CCOCC3)c2C1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.48
▸ CREBBP Q92793 17/20 0.47
▸ EP300 Q09472 14/20 0.47
▸ BRD4 O60885 4/20 0.47
▸ RBP4 P02753 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17785571 0.88 DPP4 (0.37) MAPK1CREBBPEP300BRD4RBP4
SCHEMBL14970384 0.80 RBP4 (0.50) MAPK1CREBBPEP300BRD4RBP4
SCHEMBL17868689 0.78 USP2 (0.38) RBP4
SCHEMBL17878046 0.75 NPC1 (0.50) CREBBPEP300
SCHEMBL30993458 0.75 USP2 (0.42) RBP4
SCHEMBL31566198 0.74 MAPK1 (0.39) MAPK1CREBBPEP300BRD4RBP4
SCHEMBL14970405 0.74 CREBBP (0.59) MAPK1CREBBPEP300BRD4
SCHEMBL17785625 0.73 MAPK1 (0.56) MAPK1CREBBPEP300BRD4
SCHEMBL17795280 0.73 MAPK1 (0.60) MAPK1CREBBPEP300BRD4
SCHEMBL21255655 0.73 MAPK1 (0.56) MAPK1CREBBPEP300BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090317-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2026-04-30 — — WO disclosed
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