SCHEMBL34471493

SCHEMBL34471493

CNC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C1CC1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ AAK1 Q2M2I8 3/20 0.37
▸ CTSL P07711 1/20 0.36
▸ VHL P40337 2/20 0.36
▸ ELANE P08246 4/20 0.35
▸ CHRM2 P08172 1/20 0.35
▸ CHRM1 P11229 1/20 0.35
▸ CHRM3 P20309 1/20 0.35
▸ ATM Q13315 1/20 0.34
▸ HTRA1 Q92743 1/20 0.34
▸ HDAC8 Q9BY41 2/20 0.33
▸ HDAC1 Q13547 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34472136 0.88 ATM (0.48) CYP1A2POLBCYP3A4CYP2C19AAK1
SCHEMBL24441116 0.84 CTSL (0.43) CYP1A2POLBCYP3A4CYP2C19CTSL
SCHEMBL8063520 0.83 ATM (0.45) AAK1CTSLELANEATMHDAC1
SCHEMBL13259709 0.83 ATM (0.45) AAK1CTSLELANEATMHDAC1
SCHEMBL34471083 0.83 ELANE (0.41) CYP1A2POLBCYP3A4CYP2C19VHL
SCHEMBL13259710 0.82 ALDH1A1 (0.54) CYP1A2POLBCYP3A4CYP2C19AAK1
SCHEMBL34471517 0.78 CTSL (0.55) POLBCTSLATM
SCHEMBL29044251 0.77 POLB (0.58) CYP1A2POLBCYP3A4CYP2C19VHL
SCHEMBL24441127 0.77 POLB (0.58) CYP1A2POLBCYP3A4CYP2C19VHL
SCHEMBL29044252 0.77 POLB (0.58) CYP1A2POLBCYP3A4CYP2C19VHL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090317-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2026-04-30 — — WO disclosed
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