SCHEMBL34472003

SCHEMBL34472003

O=[N+]([O-])c1c(Br)ccc2nsnc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.60
TXNRD1 Q16881 3/20 0.51
TXNRD3 Q86VQ6 3/20 0.51
TXNRD2 Q9NNW7 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.46
THRB P10828 1/20 0.46
HPGD P15428 1/20 0.46
TYMS P04818 1/20 0.40
GAA P10253 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PMM2 O15305 1/20 0.39
MPI P34949 1/20 0.39
PTPN11 Q06124 1/20 0.38
LMNA P02545 1/20 0.38
KDM4E B2RXH2 2/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5707397 0.79 MAPT (0.65) MAPTTXNRD1TXNRD3TXNRD2L3MBTL1
SCHEMBL5707241 0.79 MAPT (0.60) MAPTTXNRD1TXNRD3TXNRD2L3MBTL1
SCHEMBL26776029 0.79 MAPT (0.60) MAPTTXNRD1TXNRD3TXNRD2L3MBTL1
SCHEMBL3419143 0.79 MAPT (0.60) MAPTTXNRD1TXNRD3TXNRD2L3MBTL1
SCHEMBL5707443 0.76 MAPT (0.56) MAPTTXNRD1TXNRD3TXNRD2L3MBTL1
SCHEMBL5708726 0.75 KMT2A (0.47) MAPTTXNRD1TXNRD3TXNRD2L3MBTL1
SCHEMBL25637697 0.74 MEN1 (0.63) MAPTTYMSPMM2MPIKDM4E
SCHEMBL5707277 0.72 MAPT (0.52) MAPTTXNRD1TXNRD3TXNRD2L3MBTL1
SCHEMBL5707273 0.72 MAPT (0.52) MAPTTXNRD1TXNRD3TXNRD2L3MBTL1
SCHEMBL3469093 0.72 ALDH1A1 (0.44) TYMSPMM2MPILMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026086928-A1 SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd. (KY) 2026-04-30 WO disclosed