Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.51 |
| ▸ | TXNRD3 | Q86VQ6 | 2/20 | 0.51 |
| ▸ | TXNRD2 | Q9NNW7 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34472003 | 0.79 | MAPT (0.60) | MAPTTXNRD1TXNRD3TXNRD2MEN1 | |
| SCHEMBL26776029 | 0.79 | MAPT (0.60) | MAPTTXNRD1TXNRD3TXNRD2MEN1 | |
| SCHEMBL5707241 | 0.79 | MAPT (0.60) | MAPTTXNRD1TXNRD3TXNRD2MEN1 | |
| SCHEMBL3419143 | 0.79 | MAPT (0.60) | MAPTTXNRD1TXNRD3TXNRD2GAA | |
| SCHEMBL3180323 | 0.76 | TXNRD1 (0.60) | MAPTTXNRD1TXNRD3TXNRD2MEN1 | |
| SCHEMBL5707443 | 0.76 | MAPT (0.56) | MAPTTXNRD1TXNRD3TXNRD2MEN1 | |
| SCHEMBL3619569 | 0.75 | MAPT (0.44) | MAPTTXNRD1TXNRD3TXNRD2MEN1 | |
| SCHEMBL18083000 | 0.74 | ALDH1A1 (0.54) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18083010 | 0.74 | MEN1 (0.68) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5707273 | 0.72 | MAPT (0.52) | MAPTTXNRD1TXNRD3TXNRD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718628-A1 | CINNAMIC AMIDES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Active Biotech AB (SE) | 2006-11-08 | — | — | EP | disclosed |
| US-20050192289-A1 | Novel cinnamic amides | ACTIVE BIOTECH AB (SE) | 2005-09-01 | — | — | US | disclosed |
| WO-2005080362-A1 | CINNAMIC AMIDES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ACTIVE BIOTECH AB (SE) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192289-A1 | Novel cinnamic amides | NFATC1, H1-5, HDAC1 | MAPT 3799/4885TXNRD1 2550/4885TXNRD3 4579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.