SCHEMBL34472754

SCHEMBL34472754

COC(=O)c1cnc(NCCO)nc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 4/20 0.46
KDM4E B2RXH2 2/20 0.45
GLA P06280 1/20 0.45
EIF2AK2 P19525 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TSHR P16473 1/20 0.42
VNN1 O95497 3/20 0.42
POLB P06746 1/20 0.41
HDAC3 O15379 3/20 0.40
HDAC1 Q13547 3/20 0.40
HDAC2 Q92769 3/20 0.40
HDAC6 Q9UBN7 3/20 0.40
CYP4A11 Q02928 2/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
MAPT P10636 1/20 0.40
CYP4F2 P78329 1/20 0.39
ATM Q13315 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17676668 0.86 HCAR3 (0.47) MAPK1KDM4EL3MBTL1VNN1HDAC3
SCHEMBL23094523 0.82 HDAC3 (0.42) MAPK1VNN1HDAC3HDAC1HDAC2
SCHEMBL19609085 0.82 MAPK1 (0.49) MAPK1KDM4EGLAL3MBTL1TSHR
SCHEMBL34473202 0.81 P2RX3 (0.42) MAPK1KDM4EL3MBTL1VNN1HDAC3
SCHEMBL20431251 0.76 BCHE (0.44) MEN1GAAKMT2A
SCHEMBL20924281 0.76 MEN1 (0.48) MAPK1KDM4EL3MBTL1VNN1MEN1
SCHEMBL19776257 0.75 MAPK1 (0.49) MAPK1KDM4EL3MBTL1TSHRPOLB
SCHEMBL16769968 0.74 MAPK1 (0.52) MAPK1KDM4EL3MBTL1TSHRPOLB
SCHEMBL13393612 0.74 MAPK1 (0.52) MAPK1KDM4EEIF2AK2POLBMEN1
SCHEMBL23031061 0.74 MAPK1 (0.55) MAPK1KDM4EL3MBTL1TSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087442-A1 AMINO-IMIDAZOLE ANTIBACTERIAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2026-04-30 WO disclosed