SCHEMBL3448487

SCHEMBL3448487

CCOC(=O)OCCN1C(=O)C=CC1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.56
GSK3B P49841 1/20 0.56
MGLL Q99685 6/20 0.50
ALDH1A1 P00352 6/20 0.49
HPGD P15428 4/20 0.49
BLM P54132 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C19 P33261 1/20 0.49
WRN Q14191 1/20 0.49
HIF1A Q16665 1/20 0.49
NPSR1 Q6W5P4 4/20 0.47
LMNA P02545 3/20 0.47
MAPT P10636 3/20 0.47
GMNN O75496 1/20 0.47
THPO P40225 1/20 0.47
PMP22 Q01453 1/20 0.47
PTGS1 P23219 7/20 0.43
PTGS2 P35354 7/20 0.43
FAAH O00519 3/20 0.43
HTT P42858 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL861954 0.91 MGLL (0.59) GSK3AGSK3BMGLLALDH1A1HPGD
SCHEMBL14480521 0.89 MGLL (0.50) GSK3AGSK3BMGLLALDH1A1HPGD
SCHEMBL14890967 0.84 MGLL (0.68) GSK3AGSK3BMGLLALDH1A1HPGD
SCHEMBL31275366 0.83 MGLL (0.69) GSK3AGSK3BMGLLALDH1A1HPGD
SCHEMBL8887339 0.81 MGLL (0.53) GSK3AGSK3BMGLLALDH1A1HPGD
SCHEMBL12583863 0.80 ALDH1A1 (0.70) GSK3AGSK3BMGLLALDH1A1HPGD
SCHEMBL7096979 0.79 MGLL (0.58) GSK3AGSK3BMGLLALDH1A1HPGD
SCHEMBL3173590 0.79 MGLL (0.55) GSK3AGSK3BMGLLALDH1A1HPGD
SCHEMBL3449751 0.79 MGLL (0.47) GSK3AGSK3BMGLLALDH1A1HPGD
SCHEMBL5361313 0.78 MGLL (0.61) GSK3AGSK3BMGLLALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069891-A Liquid repellent, active energy ray-curable composition, cured product, and display device DIC株式会社 2023-11-17 CN disclosed
CN-112334501-B Fluorine-based copolymer, water-repellent surface modifier, curable resin composition, and water-repellent coating film DIC株式会社 2022-09-27 CN disclosed
CN-110446739-B Fluoroacetophenone-containing derivative, fluorine-containing additive, curable composition containing the same, and cured product thereof DIC株式会社 2022-01-11 CN disclosed
CN-110325592-B Aqueous resin composition, laminate using same, optical film, and image display device DIC株式会社 2021-09-21 CN disclosed
EP-1952184-B1 PHOTOCHROMIC MULTIFOCAL OPTICAL ARTICLE TRANSITIONS OPTICAL INC (US) 2021-08-11 EP disclosed
CN-112334501-A Fluorine-based copolymer, water-repellent surface modifier, curable resin composition, and water-repellent coating film DIC株式会社 2021-02-05 CN disclosed
EP-2554554-B1 CURABLE FLUORINE-CONTAINING RESIN AND ACTIVE ENERGY RAY CURABLE COMPOSITION USING SAME DAINIPPON INK & CHEMICALS (JP) 2015-04-29 EP disclosed
CN-102971391-B Fluorine-based surfactant, and coating composition and resist composition each using same DIC CORP. (JP) 2014-10-22 CN disclosed
CN-102834421-B Fluorine-containing curable resin and active energy ray-curable composition using same DAINIPPON INK & CHEMICALS 2014-09-24 CN disclosed
US-8779065-B2 Fluorine-containing curable resin, active energy beam-curable composition, and cured product thereof DIC CORPORATION (JP) 2014-07-15 US disclosed
US-6835758-B2 Water compatible energy curable compositions containing malemide derivatives SUN CHEMICAL CORPORATION 2004-12-28 US disclosed
US-20040127596-A1 Water compatible energy curable compositions containing malemide derivatives SUN CHEMICAL CORPORATION 2004-07-01 US disclosed
US-20040110859-A1 Water compatible energy curable compositions containing malemide derivatives SUN CHEMICAL CORPORATION 2004-06-10 US disclosed
US-20040110858-A1 Water compatible energy curable compositions containing malemide derivatives SUN CHEMICAL CORPORAITON 2004-06-10 US disclosed
US-6706777-B1 CAN BE CURED IN THE ABSENCE OF A PHOTOINITIATOR WITH A IRRADIATION SOURCE OF PRACTICAL INTENSITY AND ENERGY VALUE SUN CHEMICAL CORPORATION 2004-03-16 US disclosed
WO-2004014970-A1 PHOTOCURABLE COMPOSITION CONTAINING MALEIDE DERIVATIVES 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-02-19 WO disclosed
US-20040029044-A1 Photocurable composition 3M INNOVATIVE PROPERTIES COMPANY 2004-02-12 US disclosed
EP-0878482-B1 An active energy ray curable composition comprised of a maleimide derivative and a method for curing the said curable composition DAINIPPON INK & CHEMICALS (JP) 2003-03-26 EP disclosed
US-6410611-B1 COATINGS, SURFACE FINISHES, BINDERS DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-06-25 US disclosed
EP-0878482-A1 An active energy ray curable composition comprised of a maleimide derivative and a method for curing the said curable composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-11-18 EP disclosed