Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19388173 | 0.81 | ALDH1A1 (0.43) | PTGS1ALDH1A1MAPTSLC1A1SLC1A3 | |
| SCHEMBL20960490 | 0.78 | PTGS1 (0.54) | PTGS1ALDH1A1MAPTSLC1A1SLC1A3 | |
| SCHEMBL9450997 | 0.77 | CPT2 (0.34) | — | |
| SCHEMBL30170381 | 0.77 | ALOX15 (0.38) | ALDH1A1LMNAHSD17B10GRIN2DGRIN3B | |
| SCHEMBL28705428 | 0.76 | PTGS1 (0.52) | PTGS1ALDH1A1MAPTSLC1A1SLC1A3 | |
| SCHEMBL3821550 | 0.76 | ALDH1A1 (0.52) | PTGS1ALDH1A1MAPTSLC1A1SLC1A3 | |
| SCHEMBL4956090 | 0.76 | PTGS1 (0.52) | PTGS1ALDH1A1MAPTSLC1A1SLC1A3 | |
| SCHEMBL1631413 | 0.76 | ALDH1A1 (0.52) | PTGS1ALDH1A1MAPTSLC1A1SLC1A3 | |
| SCHEMBL4851556 | 0.76 | PTGS1 (0.52) | PTGS1ALDH1A1MAPTSLC1A1SLC1A3 | |
| SCHEMBL9451010 | 0.76 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820673-B2 | Urea derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-26 | — | — | US | disclosed |
| US-20070093501-A1 | Urea derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-04-26 | — | — | US | disclosed |
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-5182370-A | Diagnostic NMR imaging | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1993-01-26 | — | — | US | disclosed |
| US-4980502-A | For nuclear magnetic resonance imaging | BRACCO INDUSTRIA CHIMICA, S.P.A. (IT) | 1990-12-25 | — | — | US | disclosed |
| EP-0230893-B1 | PARAMAGNETIC CHELATES | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1990-06-13 | — | — | EP | disclosed |
| US-4916246-A | Paramagnetic chelates useful for NMR imaging | BRACCO CHIMICA S.P.A. (IT) | 1990-04-10 | — | — | US | disclosed |
| EP-0230893-A2 | Paramagnetic chelates | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1987-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093501-A1 | Urea derivative, process for producing the same, and use | F2, URB2, F12 | PTGS1 1660/4885ALDH1A1 3712/4885MAPT 4264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.