Flavone

Flavone

SCHEMBL344911

O=c1cc(-c2ccccc2)oc2ccccc12.OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 8/20 0.62
PARP1 P09874 4/20 0.62
TNKS2 Q9H2K2 4/20 0.62
GABRP O00591 3/20 0.62
GABRD O14764 3/20 0.62
GABRA1 P14867 3/20 0.62
GABRB1 P18505 3/20 0.62
GABRG2 P18507 3/20 0.62
GABRB3 P28472 3/20 0.62
GABRA5 P31644 3/20 0.62
GABRA3 P34903 3/20 0.62
GABRA2 P47869 3/20 0.62
GABRB2 P47870 3/20 0.62
GABRA4 P48169 3/20 0.62
GABRE P78334 3/20 0.62
GABRA6 Q16445 3/20 0.62
GABRG1 Q8N1C3 3/20 0.62
GABRG3 Q99928 3/20 0.62
GABRQ Q9UN88 3/20 0.62
HPGD P15428 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flavone SCHEMBL29013778 1.00 TNKS (0.62) TNKSPARP1TNKS2GABRPGABRD
Flavone SCHEMBL28655692 1.00 TNKS (0.62) TNKSPARP1TNKS2GABRPGABRD
SCHEMBL4156179 0.84 SLC5A2 (0.57) TNKSGABRPGABRDGABRA1GABRB1
Flavone SCHEMBL6561748 0.83 TNKS (0.62) TNKSPARP1TNKS2GABRPGABRD
Flavone SCHEMBL21823959 0.83 TNKS (0.62) TNKSPARP1TNKS2GABRPGABRD
SCHEMBL16331082 0.82 SMN1; SMN2 (0.64) TNKSHPGDNPC1RAB9ASMN1; SMN2
SCHEMBL4649434 0.80 HSD17B10 (0.66) HPGDNPC1RAB9ASMN1; SMN2CA12
SCHEMBL11304299 0.80 HSD17B10 (0.66) HPGDNPC1RAB9ASMN1; SMN2CA12
Flavone SCHEMBL28639664 0.80 TNKS (0.96) TNKSPARP1TNKS2GABRPGABRD
SCHEMBL17237764 0.80 SLC5A2 (0.45) HPGDKDM4ETDP1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116855466-A Flavonoid rutinoside biosynthesis related 1,6 rhamnosyl transferase and application thereof 浙江大学 2023-10-10 CN claimed
US-10806744-B2 Edible composition CONOPCO, INC. (US) 2020-10-20 US claimed
CN-111039998-A Preparation method of 8-benzenesulfonyl substituted flavone glucose glycoside 江南大学 2020-04-21 CN claimed
CN-110819482-A Soap composition with combined antibacterial and skin-care effects and preparation method and application thereof 上海制皂有限公司 2020-02-21 CN claimed
EP-3344070-B1 EDIBLE COMPOSITION UNILEVER PLC (GB) 2019-12-18 EP claimed
US-20180256620-A1 EDIBLE COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2018-09-13 US claimed
EP-3344070-A1 EDIBLE COMPOSITION Unilever PLC (GB) 2018-07-11 EP claimed
WO-2017036926-A1 EDIBLE COMPOSITION UNILEVER PLC (GB) 2017-03-09 WO claimed
CN-106324167-A Method for determining flavone components in radix astragali extract by UPLC (ultra performance liquid chromatography) 天津天士力现代中药资源有限公司 2017-01-11 CN claimed
CN-105954435-A Method for establishing fingerprint spectrum of Shenkangning capsules 江西普正制药有限公司 2016-09-21 CN claimed
CN-1814094-A Fat-reducing health-care product BIN XIAOHUI (CN) 2006-08-09 CN claimed
EP-1214085-B1 AN ANTIOXIDANT PREPARATION BASED ON PLANT EXTRACTS FOR THE TREATMENT OF CIRCULATION AND CHRONIC DEGENERATIVE PROBLEMS AND OF HYPERTENSION CETERIS HOLDING B V AMSTERDAM (CH) 2005-01-26 EP claimed
CN-1475222-A Vine leaf extract and its preparation process 曹 凯 2004-02-18 CN claimed
CN-1435424-A High content ginkgo extract and process for producing same SHI YANYU (CN) 2003-08-13 CN claimed
CN-1342473-A Chewing gingko leaf tablet and its preparing process DING DACHUAN (CN) 2002-04-03 CN claimed
CN-1294132-A Process for preparing total flavone glucoside of epimedium CHENGDU INST BIOLOGY CAS (CN) 2001-05-09 CN claimed
CN-1271585-A Multifunctional nutritive isomaltoligose syrup TONG ZHONGLIANG (CN) 2000-11-01 CN claimed
CN-1249334-A Process for making ginkgo-grape wine MO CHENGPENG (CN) 2000-04-05 CN claimed
CN-1151846-A Healthy ginkgo beverage BAONING PHARMACEUTICAL FACTORY (CN) 1997-06-18 CN claimed
CN-1142379-A Capsule of ginkgo leaves JIANG XUGUANG (CN) 1997-02-12 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180256620-A1 EDIBLE COMPOSITION SLC5A2, SLC2A2, SLC2A1 TNKS 4757/4885PARP1 3982/4885TNKS2 4133/4885
US-10806744-B2 Edible composition SLC5A2, SLC2A2, SLC2A1 TNKS 4757/4885PARP1 3982/4885TNKS2 4133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.