Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 10/20 | 0.62 |
| ▸ | GABRP | O00591 | 4/20 | 0.62 |
| ▸ | GABRD | O14764 | 4/20 | 0.62 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.62 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.62 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.62 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.62 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.62 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.62 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.62 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.62 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.62 |
| ▸ | GABRE | P78334 | 4/20 | 0.62 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.62 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.62 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.62 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.62 |
| ▸ | PARP1 | P09874 | 4/20 | 0.62 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flavone SCHEMBL6561748 | 1.00 | TNKS (0.62) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL28655692 | 0.83 | TNKS (0.62) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL29013778 | 0.83 | TNKS (0.62) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL344911 | 0.83 | TNKS (0.62) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Baicalein SCHEMBL28870586 | 0.81 | ABCB1 (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Flavone SCHEMBL31316377 | 0.79 | TNKS (1.00) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL30542161 | 0.79 | TNKS (1.00) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL18879 | 0.79 | TNKS (1.00) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL15676601 | 0.79 | TNKS (1.00) | TNKSGABRPGABRDGABRA1GABRB1 | |
| Flavone SCHEMBL28248986 | 0.79 | TNKS (1.00) | TNKSGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220143058-A1 | Pharmaceutical Compositions Comprising a Hydroxyethylquercetin Glucuronide | JANSSEN PHARMACEUTICA NV (BE) | 2022-05-12 | — | — | US | disclosed |
| EP-3860617-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A HYDROXYETHYLQUERCETIN GLUCURONIDE | Janssen Pharmaceutica N.V. (BE) | 2021-08-11 | — | — | EP | disclosed |
| US-20200155584-A1 | Pharmaceutical Compositions Comprising a Hydroxyethylquercetin Glucuronide | JANSSEN PHARMACEUTICA NV (BE) | 2020-05-21 | — | — | US | disclosed |
| US-10639294-B2 | Pharmaceutical compositions comprising a hydroxyethylquercetin glucuronide metabolite | JANSSEN PHARMACEUTICA NV (BE) | 2020-05-05 | — | — | US | disclosed |
| WO-2020070643-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A HYDROXYETHYLQUERCETIN GLUCURONIDE | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-09 | — | — | WO | disclosed |
| US-20200101040-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A HYDROXYETHYLQUERCETIN GLUCURONIDE METABOLITE | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | US | disclosed |
| CN-104800414-B | The separation method of general flavone glucuronide and total benzyl carbinol glycosides in callicarpa kwangtungensis Chun | 江苏康缘药业股份有限公司 | 2019-03-26 | — | — | CN | disclosed |
| CN-106606507-A | Applications of flavone diglucuronide compound in preparing cyclooxygenase inhibitors | 上海医药工业研究院 | 2017-05-03 | — | — | CN | disclosed |
| CN-104800414-A | Method for separating total flavonoid glucuronide and total phenylethanoid glycoside in Callicarpa kwangtungensis Chun | SHANGHAI INST PHARM INDUSTRY | 2015-07-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220143058-A1 | Pharmaceutical Compositions Comprising a Hydroxyethylquercetin Glucuronide | COMT, UGT1A6, SLC6A2 | TNKS 4314/4885GABRP 753/4885GABRD 593/4885 |
| US-10639294-B2 | Pharmaceutical compositions comprising a hydroxyethylquercetin glucuronide metabolite | UGT1A7, COMT, UGT1A6 | TNKS 4216/4885GABRP 1114/4885GABRD 628/4885 |
| US-20200155584-A1 | Pharmaceutical Compositions Comprising a Hydroxyethylquercetin Glucuronide | COMT, UGT1A6, SLC6A2 | TNKS 4314/4885GABRP 753/4885GABRD 593/4885 |
| US-20200101040-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A HYDROXYETHYLQUERCETIN GLUCURONIDE METABOLITE | UGT1A7, COMT, UGT1A6 | TNKS 4216/4885GABRP 1114/4885GABRD 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.