Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 11/20 | 0.48 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 3/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3448621 | 0.98 | P2RY12 (0.48) | P2RY12PAK1FGFR1EGFRERBB2 | |
| SCHEMBL3449923 | 0.98 | P2RY12 (0.47) | P2RY12PAK1FGFR1EGFRERBB2 | |
| SCHEMBL3448014 | 0.98 | P2RY12 (0.47) | P2RY12PAK1FGFR1EGFRERBB2 | |
| SCHEMBL3447080 | 0.94 | PAK1 (0.53) | P2RY12PAK1FGFR1EGFRBRD4 | |
| SCHEMBL3448416 | 0.93 | P2RY12 (0.46) | P2RY12PAK1FGFR1EGFRERBB2 | |
| SCHEMBL3449965 | 0.93 | P2RY12 (0.46) | P2RY12PAK1FGFR1EGFRERBB2 | |
| SCHEMBL3448122 | 0.93 | P2RY12 (0.46) | P2RY12PAK1EGFRBRD4PTK2 | |
| SCHEMBL3452344 | 0.92 | P2RY12 (0.51) | P2RY12PAK1 | |
| SCHEMBL3458418 | 0.91 | P2RY12 (0.45) | P2RY12PAK1FGFR1EGFRERBB2 | |
| SCHEMBL3449108 | 0.91 | P2RY12 (0.46) | P2RY12PAK1FGFR1BRD4AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137313-A1 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB | 2010-06-03 | — | — | US | disclosed |
| US-20100137313-A1 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB | 2010-06-03 | — | — | US | disclosed |
| US-20100137313-A1 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137313-A1 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | SDHA, SDHB, UROD | P2RY12 2175/4885PAK1 2792/4885FGFR1 3917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.