Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.52 |
| ▸ | MIF | P14174 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3450462 | 1.00 | CYP19A1 (0.56) | CYP19A1CYP11B2CYP11B1MIFKDM4E | |
| SCHEMBL3018271 | 0.91 | MIF (0.57) | CYP19A1CYP11B2CYP11B1MIFKDM4E | |
| SCHEMBL3018274 | 0.91 | MIF (0.57) | CYP19A1CYP11B2CYP11B1MIFKDM4E | |
| SCHEMBL9391395 | 0.91 | MIF (0.57) | CYP19A1CYP11B2CYP11B1MIFKDM4E | |
| SCHEMBL12695711 | 0.89 | NQO2 (0.49) | CYP19A1CYP11B2CYP11B1KDM4ERXRA | |
| SCHEMBL3894416 | 0.89 | NQO2 (0.49) | CYP19A1CYP11B2CYP11B1KDM4ERXRA | |
| SCHEMBL3894420 | 0.89 | NQO2 (0.49) | CYP19A1CYP11B2CYP11B1KDM4ERXRA | |
| SCHEMBL3854161 | 0.87 | MAOA (0.53) | CYP19A1CYP11B2RXRAMAPTALDH1A1 | |
| SCHEMBL14137061 | 0.83 | MIF (0.65) | CYP19A1MIFKDM4ECYP26A1MAPT | |
| SCHEMBL4975289 | 0.83 | MIF (0.65) | CYP19A1MIFKDM4ECYP26A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820837-B2 | ethyl {6-[(3-phenoxybenzyl)oxy]-3,4-dihydronaphthalen-1-yl}acetate; having a GPR40 receptor function modulating action and being useful as an insulin secretagogue or a pharmaceutical agent for the prophylaxis or treatment of diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-26 | — | — | US | disclosed |
| EP-1630152-A1 | CONDENSED RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2006-03-01 | — | — | EP | disclosed |
| US-5192797-A | Antiepileptic and anticonvulsant agents | SYNTHELABO (FR) | 1993-03-09 | — | — | US | disclosed |