Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PEPD | P12955 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL7565074 | 0.96 | SLC34A1 (0.47) | SLC34A1LMNACA1CA2CA9 | |
| Phosphoric Acid SCHEMBL27204660 | 0.92 | SLC34A1 (0.50) | SLC34A1LMNACA1CA2CA9 | |
| Phosphoric Acid SCHEMBL28159823 | 0.92 | SLC34A1 (0.50) | SLC34A1LMNACA1CA2CA9 | |
| Phosphoric Acid SCHEMBL9078852 | 0.92 | SLC34A1 (0.50) | SLC34A1LMNACA1CA2CA9 | |
| Phosphoric Acid SCHEMBL2908514 | 0.92 | SLC34A1 (0.50) | SLC34A1LMNACA1CA2CA9 | |
| Phosphoric Acid SCHEMBL6070608 | 0.92 | SLC34A1 (0.61) | SLC34A1LMNACA1CA2CA9 | |
| Phosphoric Acid SCHEMBL5908781 | 0.92 | LMNA (0.50) | SLC34A1LMNACA1CA2CA9 | |
| Phosphoric Acid SCHEMBL28200678 | 0.89 | SLC34A1 (0.41) | SLC34A1LMNACA1CA2CA9 | |
| Phosphoric Acid SCHEMBL5614383 | 0.88 | SLC34A1 (0.57) | SLC34A1LMNACA1CA2CA9 | |
| Phosphoric Acid SCHEMBL16713064 | 0.88 | SLC34A1 (0.57) | SLC34A1LMNACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505597-B1 | HALOGEN-FREE FIXED FLAME RETARDANT MIXTURE AND ITS USE | CLARIANT INT LTD (CH) | 2022-08-31 | — | — | EP | claimed |
| CN-108764594-B | Stability index system of water supply pipe network and evaluation method thereof | 深圳市水务(集团)有限公司 | 2022-03-11 | — | — | CN | claimed |
| US-20200121271-A1 | Medical Grid with Bar Codes | DAVIS RANDALL PAUL (US) | 2020-04-23 | — | — | US | claimed |
| US-20160340588-A1 | Halogen-Free Solid Flame Retardant Mixture And Use Thereof | CLARIANT INTERNATIONAL LTD. (CH) | 2016-11-24 | — | — | US | claimed |
| US-20120067748-A1 | Prophylaxis Paste Holder Dispenser with Multiple Prophylaxis Pastes | YOUNG DENTAL MANUFACTURING COMPANY 1, LLC | 2012-03-22 | — | — | US | claimed |
| EP-1761472-B1 | MACROPOROUS, RESORBABLE AND INJECTIBLE CALCIUM PHOSPHATE-BASED CEMENTS (MCPC) FOR BONE REPAIR, AUGMENTATION, REGENERATION, AND OSTEOPOROSIS TREATMENT | UNIV NEW YORK (US) | 2011-05-11 | — | — | EP | claimed |
| US-20110046262-A1 | Pasty Insert Material for Widening of Gingival Sulcus and Use Thereof | KETTENBACH GMBH & CO. KG (DE) | 2011-02-24 | — | — | US | claimed |
| US-7850453-B2 | Reshapable device for fixation at a dental site | COLL PARTNERS LTD. (VG) | 2010-12-14 | — | — | US | claimed |
| US-20090317339-A1 | Teeth Bleaching Compositions and Devices | MCNEIL-PPC, INC. | 2009-12-24 | — | — | US | claimed |
| US-20090042161-A1 | Reshapable device for fixation at a dental site | COLLDENT Y.A. LTD. (IL) | 2009-02-12 | — | — | US | claimed |
| EP-0987031-B1 | Method for coating medical implants | ISOTIS NV (NL) | 2003-04-02 | — | — | EP | claimed |
| US-20010053406-A1 | Coating an implantable device with a thin, dense and bioactive layer of carbonated calcium phosphate. | ISOTIS B.V. (NL) | 2001-12-20 | — | — | US | claimed |
| US-20010008649-A1 | Method for coating medical implants | ISO TIS B.V. (NL) | 2001-07-19 | — | — | US | claimed |
| US-6207218-B1 | CONTACTING IMPLANT WITH AQUEOUS SOLUTION OF MAGNESIUM, CALCIUM, PHOSPHATE IONS, PASSING GASEOUS WEAK ACID THROUGH AQUEOUS SOLUTION TO MAINTAIN CONCENTRATED SOLUTION OF IONS, DEGASSING TO PRECIPITATE MAGNESIUM, CALCIUM, PHOSPHATE IONS | ISOTIS B.V. (NL) | 2001-03-27 | — | — | US | claimed |
| EP-0987031-A1 | Method for coating medical implants | Isotis B.V. (NL) | 2000-03-22 | — | — | EP | claimed |
| US-6000341-A | Methods and composition for mineralizing and fluoridating calcified tissues | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1999-12-14 | — | — | US | claimed |
| US-5437857-A | A deposited apatite is formed on teeth in situ after applying a mixed solution of amorphous calcium compound and a material forming amorphous calcium phosphate, calcium phosphate fluoride or calcium carbonate phosphate | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1995-08-01 | — | — | US | claimed |
| EP-0628017-A1 | METHODS AND COMPOSITIONS FOR MINERALIZING AND FLUORIDATING CALCIFIED TISSUES | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1994-12-14 | — | — | EP | claimed |
| WO-1994004460-A1 | METHODS AND COMPOSITIONS FOR MINERALIZING AND FLUORIDATING CALCIFIED TISSUES | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1994-03-03 | — | — | WO | claimed |
| US-5268167-A | Dental restorative; amorphous calcium phosphate fluoride and carrier | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1993-12-07 | — | — | US | claimed |