Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.73 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.61 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904514 | 0.85 | ADORA2A (1.00) | ADORA2AADORA1MEN1KMT2ALMNA | |
| SCHEMBL716998 | 0.84 | ADORA2A (0.50) | ADORA2AADORA1MEN1KMT2ALMNA | |
| SCHEMBL19417246 | 0.81 | ADORA2A (0.91) | ADORA2AADORA1MEN1KMT2ALMNA | |
| SCHEMBL3450486 | 0.81 | MEN1 (0.47) | ADORA2AADORA1MEN1KMT2ALMNA | |
| SCHEMBL18931741 | 0.81 | KDM4E (0.58) | ADORA2AADORA1MEN1KMT2ALMNA | |
| SCHEMBL3451384 | 0.81 | KDM4E (0.60) | ADORA2AADORA1MEN1KMT2ALMNA | |
| SCHEMBL8995844 | 0.80 | MAP4K4 (0.52) | ADORA2AADORA1KDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL20019135 | 0.80 | ADORA2A (0.80) | ADORA2AADORA1MEN1KMT2ALMNA | |
| SCHEMBL3451123 | 0.79 | MEN1 (0.52) | ADORA2AADORA1MEN1KMT2ALMNA | |
| SCHEMBL3307656 | 0.79 | MEN1 (0.68) | ADORA2AADORA1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116103008-B | Strippable polyurethane hot melt adhesive based on reactive extrusion and synthesis method thereof | 郑州大学 | 2025-03-21 | — | — | CN | claimed |
| CN-116376507-A | Ureido pyrimidinone modified polyethyleneimine adhesive and synthetic method thereof | 郑州大学 | 2023-07-04 | — | — | CN | claimed |
| CN-114716961-B | Self-complementary quadruple hydrogen bond supermolecule hot melt adhesive and synthesis method thereof | 郑州大学 | 2023-06-23 | — | — | CN | claimed |
| CN-116103008-A | Strippable polyurethane hot melt adhesive based on reactive extrusion and synthesis method thereof | 郑州大学 | 2023-05-12 | — | — | CN | claimed |
| CN-114716961-A | Self-complementary quadruple hydrogen bond supramolecular hot melt adhesive and synthesis method thereof | 郑州大学 | 2022-07-08 | — | — | CN | claimed |
| CN-108067191-A | For the reactor assembly of orthophosphates in Adsorption waste water | 北京益清源环保科技有限公司 | 2018-05-25 | — | — | CN | claimed |
| CN-108059205-A | For the up-flow adsorptive reactor of orthophosphates in Adsorption waste water | 北京益清源环保科技有限公司 | 2018-05-22 | — | — | CN | claimed |
| CN-107930577-A | There is the modified bentonite adsorbent of absorption property to the orthophosphates in water body | 北京益清源环保科技有限公司 | 2018-04-20 | — | — | CN | claimed |
| EP-1796673-A2 | NOVEL PYRIMIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | Reddy US Therapeutics, Inc. (US) | 2007-06-20 | — | — | EP | claimed |
| US-20060084645-A1 | Novel pyrimidine compounds, process for their preparation and compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-04-20 | — | — | US | claimed |
| WO-2006034473-A2 | NOVEL PYRIMIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | REDDY US THERAPEUTICS, INC. (US) | 2006-03-30 | — | — | WO | claimed |
| CN-116103008-B | Strippable polyurethane hot melt adhesive based on reactive extrusion and synthesis method thereof | 郑州大学 | 2025-03-21 | — | — | CN | disclosed |
| US-20230373935-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS, SAN DIEGO | 2023-11-23 | — | — | US | disclosed |
| EP-4225748-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | Vertex Pharmaceuticals Incorporated (US) | 2023-08-16 | — | — | EP | disclosed |
| CN-116376507-A | Ureido pyrimidinone modified polyethyleneimine adhesive and synthetic method thereof | 郑州大学 | 2023-07-04 | — | — | CN | disclosed |
| US-5002951-A | 2-amino-5-halo-4-pyrimidinol for bactericides and antiprotozoa agent | THE UPJOHN COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| US-4665077-A | IMMUNOREGULATORY AGENTS | THE UPJOHN COMPANY (US) | 1987-05-12 | — | — | US | disclosed |
| US-4619933-A | 6-aryl pyrimidines for treating aplastic anemia | THE UPJOHN COMPANY (US) | 1986-10-28 | — | — | US | disclosed |
| US-4543248-A | Method for immunoregulation with 6-aryl pyrimidine compounds | THE UPJOHN COMPANY (US) | 1985-09-24 | — | — | US | disclosed |
| US-4507302-A | Method for treating arthritis with 6-aryl pyrimidine compounds | THE UPJOHN COMPANY (US) | 1985-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084645-A1 | Novel pyrimidine compounds, process for their preparation and compositions containing them | UMPS, DPYD, TYMS | ADORA2A 1490/4885ADORA1 2067/4885MEN1 4470/4885 |
| US-20230373935-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1G, SCNN1B | ADORA2A 1622/4885ADORA1 1287/4885MEN1 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.