SCHEMBL3451683

SCHEMBL3451683

O=Cc1ccc(O)c(C=O)c1C=O

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 11/20 0.50
TRIM24 O15164 2/20 0.46
TRIM33 Q9UPN9 2/20 0.46
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
HSP90AA1 P07900 1/20 0.41
IDO1 P14902 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TYR P14679 2/20 0.41
CDK1 P06493 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29111409 0.87 ERN1 (0.56) ERN1TRIM24TRIM33KDM4ERAB9A
Fomecin B SCHEMBL11039474 0.85 ERN1 (0.54) ERN1TRIM24TRIM33KDM4EMEN1
SCHEMBL548457 0.84 TDP1 (0.50) ERN1TRIM24TRIM33MEN1KMT2A
SCHEMBL10748907 0.83 ERN1 (0.52) ERN1TRIM24TRIM33KDM4EMEN1
SCHEMBL1302180 0.78 ERN1 (0.64) ERN1TRIM24TRIM33MEN1RAB9A
SCHEMBL7939012 0.74 CA1 (0.59) ERN1TRIM24TRIM33TYR
SCHEMBL31236213 0.74 ERN1 (0.61) ERN1
SCHEMBL2790223 0.74 TRIM24 (0.50) ERN1TRIM24TRIM33KDM4EMEN1
SCHEMBL29459661 0.74 ERN1 (0.50) ERN1TRIM24TRIM33KDM4ERAB9A
SCHEMBL1002739 0.74 ERN1 (0.50) ERN1TRIM24TRIM33KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113933501-A Immunomagnetic bead and preparation method and application thereof 吉林中科研伸科技有限公司 2022-01-14 CN claimed
CN-114752028-B Solvent-free preparation method and application of covalent organic framework COFs film 广西师范大学 2023-04-18 CN disclosed
CN-115101349-A Flexible self-supporting covalent organic framework fibrous membrane and preparation method and application thereof 上海大学 2022-09-23 CN disclosed
CN-114752028-A Solvent-free preparation method and application of covalent organic framework COFs film 广西师范大学 2022-07-15 CN disclosed
CN-114713286-A Ti-MOFs @ COFs hybrid material with stable core-shell structure and preparation method and application thereof 中南大学 2022-07-08 CN disclosed
US-7858819-B2 Tris(formylphenyl) and novel polynuclear phenol derived therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2010-12-28 US disclosed
US-20100099908-A1 TRIS(FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED THEREFROM HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2010-04-22 US disclosed
EP-0044260-B1 PROCESS FOR THE PREPARATION OF POLYPHENOLS OPTIONALLY SUBSTITUTED BY AN ALDEHYDE GROUP RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-04-11 EP disclosed
US-4435601-A OXIDATION WITH HYDROGEN PEROXIDE IN ALKALI OR ALKALINE METAL BASE RHONE-POULENC INDUSTRIES (FR) 1984-03-06 US disclosed
EP-0044260-A2 Process for the preparation of polyphenols optionally substituted by an aldehyde group RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1982-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099908-A1 TRIS(FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED THEREFROM AS3MT, RRM2, SHROOM3 ERN1 3506/4885TRIM24 2466/4885TRIM33 450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.