SCHEMBL548457

SCHEMBL548457

O=Cc1ccc(C=O)c(C=O)c1C=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
LMNA P02545 1/20 0.50
THRB P10828 1/20 0.50
BLM P54132 1/20 0.50
ALDH1A1 P00352 4/20 0.41
TRIM24 O15164 2/20 0.39
TRIM33 Q9UPN9 2/20 0.39
TSHR P16473 1/20 0.39
ERN1 O75460 2/20 0.36
CCR1 P32246 1/20 0.35
CCR5 P51681 1/20 0.35
CCR8 P51685 1/20 0.35
PADI4 Q9UM07 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TYR P14679 2/20 0.34
GFER P55789 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9218398 0.86 TDP1 (0.39) TDP1MEN1KMT2ALMNATHRB
SCHEMBL5549581 0.84 TDP1 (0.43) TDP1MEN1KMT2ALMNATHRB
SCHEMBL3451683 0.84 ERN1 (0.50) MEN1KMT2ATRIM24TRIM33ERN1
SCHEMBL548044 0.84 ALDH1A1 (0.46) TDP1MEN1KMT2ALMNATHRB
SCHEMBL4127921 0.84 TDP1 (0.38) TDP1MEN1KMT2ALMNATHRB
SCHEMBL547829 0.80 KMT2A (0.61) TDP1MEN1KMT2ALMNATHRB
SCHEMBL31400023 0.80 KDM4E (0.37) TDP1MEN1KMT2ALMNATHRB
SCHEMBL548393 0.78 CYP1A2 (0.42) TDP1MEN1KMT2ALMNATHRB
Fomecin B SCHEMBL11039474 0.78 ERN1 (0.54) MEN1KMT2ATRIM24TRIM33ERN1
SCHEMBL547760 0.76 KMT2A (0.42) TDP1MEN1KMT2ALMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2808736-B1 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO (JP) 2018-07-18 EP claimed
EP-2808736-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-12-03 EP claimed
EP-2662727-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-11-13 EP claimed
CN-113004596-B Preparation method of diene dielectric elastomer 华南理工大学 2021-11-30 CN disclosed
CN-113004596-A Preparation method of diene dielectric elastomer 华南理工大学 2021-06-22 CN disclosed
EP-2080750-B1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2020-07-29 EP disclosed
EP-2808736-B1 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO (JP) 2018-07-18 EP disclosed
US-9897913-B2 Radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-02-20 US disclosed
EP-2199437-B1 Use of an organic semiconductor solution to form oriented polyacene crystals on a substrate ASAHI CHEMICAL IND (JP) 2015-07-29 EP disclosed
US-20150030980-A1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2015-01-29 US disclosed
EP-2808736-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-12-03 EP disclosed
US-20050207800-A1 Intermediate transfer medium and image forming apparatus using the intermediate transfer medium RICOH COMPANY LIMITED (JP) 2005-09-22 US disclosed
US-20050136245-A1 Intermediate transfer medium, film forming liquid for the intermediate transfer medium and image forming apparatus using intermediate transfer medium RICOH COMPANY LIMITED (JP) 2005-06-23 US disclosed
EP-1416069-A1 ORGANIC SEMICONDUCTOR ELEMENT Asahi Kasei Kabushiki Kaisha (JP) 2004-05-06 EP disclosed
EP-0548235-A4 SYNTHETIC DRUG MOLECULES THAT MIMIC METALLOENZYMES UNIV CALIFORNIA (US) 1996-08-14 EP disclosed
EP-0548235-A1 SYNTHETIC DRUG MOLECULES THAT MIMIC METALLOENZYMES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-06-30 EP disclosed
US-5217966-A Synthetic drug molecules that mimic metalloenzymes THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-06-08 US disclosed
US-5202317-A SYNTHETIC DRUG MOLECULES THAT MIMIC METALLOENZYMES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-04-13 US disclosed
WO-1992005178-A1 SYNTHETIC DRUG MOLECULES THAT MIMIC METALLOENZYMES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1992-04-02 WO disclosed
US-4505998-A Alkaline battery containing a separator of a cross-linked copolymer of vinyl alcohol and unsaturated carboxylic acid THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1985-03-19 US disclosed