Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16448979 | 0.88 | TSHR (0.66) | TSHRALDH1A1MAPTLMNAGAA | |
| SCHEMBL13108797 | 0.84 | TDP1 (0.70) | TSHRALDH1A1MAPTLMNAGAA | |
| SCHEMBL12308580 | 0.84 | TSHR (0.60) | TSHRALDH1A1MAPTLMNAGAA | |
| SCHEMBL11894104 | 0.82 | POLB (0.77) | TSHRALDH1A1MAPTLMNAGAA | |
| SCHEMBL3452458 | 0.81 | PPARD (0.64) | TSHRALDH1A1MAPTLMNAGAA | |
| SCHEMBL2775568 | 0.80 | MAPT (0.74) | TSHRALDH1A1MAPTLMNAGAA | |
| SCHEMBL16230424 | 0.79 | GHSR (0.52) | TSHRALDH1A1MAPTLMNAGAA | |
| SCHEMBL17826839 | 0.79 | TSHR (0.64) | TSHRALDH1A1MAPTLMNAGAA | |
| SCHEMBL12204325 | 0.78 | MAPT (0.67) | TSHRALDH1A1MAPTLMNAGAA | |
| SCHEMBL14185458 | 0.78 | TSHR (0.63) | TSHRALDH1A1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820705-B2 | Compounds and compositions as PPAR modulators | IRM LLC (BM) | 2010-10-26 | — | — | US | disclosed |
| US-7820705-B2 | Compounds and compositions as PPAR modulators | IRM LLC (BM) | 2010-10-26 | — | — | US | disclosed |
| US-7820705-B2 | Compounds and compositions as PPAR modulators | IRM LLC (BM) | 2010-10-26 | — | — | US | disclosed |
| EP-1745027-A4 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2009-06-03 | — | — | EP | disclosed |
| US-20080114044-A1 | Compounds And Compositions As Ppar Modulators | EPPLE ROBERT | 2008-05-15 | — | — | US | disclosed |
| EP-1745027-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM, LLC (BM) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005113519-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2005-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114044-A1 | Compounds And Compositions As Ppar Modulators | PPARG, PPARA, PPARD | TSHR 559/4885ALDH1A1 1651/4885MAPT 3464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.