Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PPARD | Q03181 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3451742 | 0.84 | TSHR (0.61) | TDP1MAPTALDH1A1GAALMNA | |
| SCHEMBL12204325 | 0.83 | MAPT (0.67) | TDP1MAPTALDH1A1GAALMNA | |
| SCHEMBL16448979 | 0.83 | TSHR (0.66) | TDP1MAPTALDH1A1GAALMNA | |
| SCHEMBL3452458 | 0.83 | PPARD (0.64) | TDP1ATMMAPTALDH1A1GAA | |
| SCHEMBL12308580 | 0.79 | TSHR (0.60) | TDP1MAPTALDH1A1GAALMNA | |
| SCHEMBL11894104 | 0.78 | POLB (0.77) | TDP1MAPTALDH1A1GAALMNA | |
| SCHEMBL3633629 | 0.76 | PTGS2 (0.64) | MAPTALDH1A1LMNATSHRPTGS2 | |
| SCHEMBL316185 | 0.76 | ALDH1A1 (0.76) | TDP1MAPTALDH1A1GAALMNA | |
| SCHEMBL2775568 | 0.75 | MAPT (0.74) | ATMMAPTALDH1A1GAALMNA | |
| SCHEMBL12584940 | 0.75 | MAPT (0.64) | MAPTALDH1A1GAALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820705-B2 | Compounds and compositions as PPAR modulators | IRM LLC (BM) | 2010-10-26 | — | — | US | disclosed |
| US-20080114044-A1 | Compounds And Compositions As Ppar Modulators | EPPLE ROBERT | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114044-A1 | Compounds And Compositions As Ppar Modulators | PPARG, PPARA, PPARD | TDP1 3465/4885ATM 1691/4885MAPT 3464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.