SCHEMBL345175

SCHEMBL345175

NOC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29163536 0.73 LMNA (0.42) LMNATHRB
SCHEMBL11511027 0.73 LMNA (0.42) LMNATHRB
SCHEMBL3629816 0.73 LMNA (0.42) LMNATHRB
SCHEMBL11509926 0.73 LMNA (0.42) LMNATHRB
SCHEMBL3313899 0.73 LMNA (0.42) LMNATHRB
SCHEMBL9589771 0.73 LMNA (0.42) LMNATHRB
SCHEMBL21355 0.73 LMNA (0.42) LMNATHRB
SCHEMBL2925447 0.73 LMNA (0.42) LMNATHRB
SCHEMBL22653573 0.73 LMNA (0.42) LMNATHRB
SCHEMBL8717900 0.73 LMNA (0.42) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9376330-B2 Water pretreatment unit using a fluorinated liquid ADIONICS (FR) 2016-06-28 US claimed
EP-2391584-B1 WATER PRETREATMENT UNIT USING A FLUORINATED LIQUID ADIONICS (FR) 2019-06-26 EP disclosed
US-10183873-B2 Water pretreatment unit using a fluorinated liquid ADIONICS (FR) 2019-01-22 US disclosed
US-20160318771-A1 WATER PRETREATMENT UNIT USING A FLUORINATED LIQUID ADIONICS (FR) 2016-11-03 US disclosed
US-9376330-B2 Water pretreatment unit using a fluorinated liquid ADIONICS (FR) 2016-06-28 US disclosed
EP-2463239-A1 Unit for pre-treating water by means of a fluorinated liquid De Souza, Guillaume (FR) 2012-06-13 EP disclosed
US-20120012529-A1 WATER PRETREATMENT UNIT USING A FLUORINATED LIQUID ADIONICS (FR) 2012-01-19 US disclosed