SCHEMBL3452359

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL250233	0.87	ERN1 (0.42)	ESR1ESR2ERN1ALOX15ALOX12
	SCHEMBL3452255	0.86	ESR1 (0.41)	ESR1ESR2ERN1PTGS1PTGS2
	SCHEMBL3452569	0.85	ESR1 (0.40)	ESR1ESR2ERN1TLR2TLR1
	SCHEMBL3452572	0.84	ESR1 (0.39)	ESR1ESR2ERN1TLR2TLR1
	SCHEMBL3451314	0.81	ESR1 (0.50)	ESR1ESR2ERN1CNR1CNR2
	SCHEMBL3453280	0.79	PTPN5 (0.36)	ESR1ESR2ERN1
	SCHEMBL237756	0.78	ESR1 (0.61)	ESR1ESR2CNR1CNR2PTGS1
	SCHEMBL2729726	0.78	ERN1 (0.47)	ERN1
	SCHEMBL9177422	0.77	ESR1 (0.50)	ESR1ESR2ERN1ALOX15ALDH1A1
	SCHEMBL9176114	0.76	ERN1 (0.58)	ERN1ALOX15ALOX12ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.