Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 10/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.31 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3452776 | 0.88 | ESR1 (0.37) | ESR1ESR2GABRA1GABRB2ALOX15 | |
| SCHEMBL3452359 | 0.85 | ESR1 (0.42) | ESR1ESR2ALOX15ERN1TLR2 | |
| SCHEMBL3452255 | 0.83 | ESR1 (0.41) | ESR1ESR2MAPK1ERN1ALOX12 | |
| SCHEMBL5026246 | 0.81 | GABRA1 (0.57) | ESR1ESR2GABRA1GABRB2ALOX15 | |
| SCHEMBL3452572 | 0.81 | ESR1 (0.39) | ESR1ESR2GABRA1GABRB2ALOX15 | |
| SCHEMBL3451314 | 0.77 | ESR1 (0.50) | ESR1ESR2ALOX15KLF10ERN1 | |
| SCHEMBL1228603 | 0.77 | CYP2C19 (0.44) | ESR1ESR2GABRA1GABRB2ERN1 | |
| SCHEMBL3453280 | 0.76 | PTPN5 (0.36) | ESR1ESR2PTPN5ERN1MAPT | |
| SCHEMBL3452130 | 0.75 | ATM (0.34) | ESR1ESR2GABRA1GABRB2ALOX15 | |
| SCHEMBL18218326 | 0.74 | ALOX15 (0.46) | ALOX15KLF10MAPK1HTTERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858819-B2 | Tris(formylphenyl) and novel polynuclear phenol derived therefrom | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-12-28 | — | — | US | disclosed |
| US-20100099908-A1 | TRIS(FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED THEREFROM | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099908-A1 | TRIS(FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED THEREFROM | AS3MT, RRM2, SHROOM3 | ESR1 132/4885ESR2 382/4885GABRA1 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.