Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of N-Methylpiperidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Methylpiperidine SCHEMBL9042506 | 0.92 | TDP1 (0.36) | — | |
| SCHEMBL18807723 | 0.92 | HRH3 (0.37) | — | |
| SCHEMBL12952612 | 0.92 | HRH3 (0.37) | — | |
| SCHEMBL12316976 | 0.92 | HRH3 (0.37) | — | |
| SCHEMBL414741 | 0.92 | HRH3 (0.37) | — | |
| SCHEMBL20124473 | 0.92 | HRH3 (0.37) | — | |
| N-Methylpiperidine SCHEMBL6660565 | 0.92 | HRH3 (0.37) | — | |
| N-Methylpiperidine SCHEMBL1920 | 0.92 | — | — | |
| SCHEMBL21960469 | 0.92 | HRH3 (0.37) | — | |
| SCHEMBL3793955 | 0.92 | HRH3 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116284848-A | Method for dissolving chitosan/cellulose by using multifunctional acidic ionic liquid | 南京工业大学 | 2023-06-23 | — | — | CN | claimed |
| US-12398098-B2 | Waterborne crosslinker composition | COVESTRO (NETHERLANDS) B.V. (NL) | 2025-08-26 | — | — | US | disclosed |
| CN-116284848-A | Method for dissolving chitosan/cellulose by using multifunctional acidic ionic liquid | 南京工业大学 | 2023-06-23 | — | — | CN | disclosed |
| US-20230193057-A1 | WATERBORNE CROSSLINKER COMPOSITION | COVESTRO (NETHERLANDS) B.V. (NL) | 2023-06-22 | — | — | US | disclosed |
| EP-4093790-A1 | WATERBORNE CROSSLINKER COMPOSITION | Covestro (Netherlands) B.V. (NL) | 2022-11-30 | — | — | EP | disclosed |
| CN-115038733-A | Aqueous cross-linker composition | 科思创(荷兰)有限公司 | 2022-09-09 | — | — | CN | disclosed |
| WO-2021148563-A1 | WATERBORNE CROSSLINKER COMPOSITION | COVESTRO (NETHERLANDS) B.V. (NL) | 2021-07-29 | — | — | WO | disclosed |
| CN-106999973-A | System and method for discharging edible material | 阿甘芳香和精细化工有限公司 | 2017-08-01 | — | — | CN | disclosed |
| EP-1741697-B1 | CRYSTAL COMPRISING (2R)-2-PROPYLOCTANOIC ACID AND DIBENZYLAMINE | ONO PHARMACEUTICAL CO (JP) | 2012-12-19 | — | — | EP | disclosed |
| US-8273916-B2 | Crystal comprising (2R)-2-propyloctanoic acid and amine | ONO PHARMACEUTICAL CO., LTD. (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20100331414-A1 | CRYSTAL COMPRISING (2R)-2-PROPYLOCTANOIC ACID AND AMINE | ONO PHARMACEUTICAL CO., LTD (JP) | 2010-12-30 | — | — | US | disclosed |
| US-7820715-B2 | Crystal comprising (2R)-2-propyloctanoic acid and amine | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-10-26 | — | — | US | disclosed |
| US-20080090907-A1 | Crystal Comprising (2R)-2-Propyloctanoic Acid and Amine | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-04-17 | — | — | US | disclosed |
| EP-1741697-A1 | CRYSTAL COMPRISING (2R)-2-PROPYLOCTOIC ACID AND AMINE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-10 | — | — | EP | disclosed |