SCHEMBL345256

SCHEMBL345256

CCC(CO)Cc1ccc(C)cc1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.39
IDO1 P14902 1/20 0.38
NR3C1 P04150 1/20 0.37
PGR P06401 1/20 0.37
NR3C2 P08235 1/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
HCRTR2 O43614 7/20 0.37
SLC6A4 P31645 1/20 0.36
ACACB O00763 1/20 0.36
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17736164 0.89 IDO1 (0.42) TRPA1IDO1HCRTR2ACACBCYP1A2
SCHEMBL15726082 0.83 PPARG (0.41) TRPA1IDO1HCRTR2ACACB
SCHEMBL12512917 0.83 ESR1 (0.55) PGRESR1ESR2CYP1A2TAAR1
SCHEMBL19038363 0.82 APP (0.37) TRPA1IDO1HCRTR2SLC6A4ACACB
SCHEMBL14003410 0.82 TRPA1 (0.58) TRPA1IDO1ESR1ESR2TAAR1
SCHEMBL344690 0.82 SLC6A2 (0.48) TRPA1IDO1ESR1ESR2SLC6A4
SCHEMBL11570604 0.82 CYP1A2 (0.44) TRPA1IDO1ESR1ESR2SLC6A4
SCHEMBL345523 0.81 TRPA1 (0.55) TRPA1IDO1SLC6A4CYP1A2CYP2A6
SCHEMBL2604925 0.81 TRPA1 (0.55) TRPA1IDO1SLC6A4CYP1A2CYP2A6
SCHEMBL13996985 0.80 TRPA1 (0.39) TRPA1IDO1HCRTR2ACACBTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210069071-A1 COSMETIC SOAP GEL STICKS WITH IMPROVED MANUFACTURABILITY HENKEL AG & CO. KGAA (DE) 2021-03-11 US claimed
EP-2453867-A2 COSMETIC AND DERMATOLOGICAL TOPICAL COMPOSITIONS HAVING A HAIR GROWTH-MINIMISING OR HAIR GROWTH-INHIBITING EFFECT Henkel AG & Co. KGaA (DE) 2012-05-23 EP claimed
EP-2349185-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A SPRAY Henkel AG & Co. KGaA (DE) 2011-08-03 EP claimed
EP-2349184-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A NON-AEROSOL Henkel AG & Co. KGaA (DE) 2011-08-03 EP claimed
WO-2011006689-A2 COSMETIC AND DERMATOLOGICAL TOPICAL COMPOSITIONS HAVING A HAIR GROWTH-MINIMISING OR HAIR GROWTH-INHIBITING EFFECT HENKEL AG & CO. KGAA (DE) 2011-01-20 WO claimed
WO-2010009977-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A SPRAY HENKEL AG & CO. KGAA (DE) 2010-01-28 WO claimed
WO-2010009976-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A NON-AEROSOL HENKEL AG & CO. KGAA (DE) 2010-01-28 WO claimed
US-11504309-B2 Deo emulsion for aerosols, deodorant comprising the same and use of the deodorant HENKEL AG & CO. KGAA (DE) 2022-11-22 US disclosed
US-11324675-B2 Deo emulsion for aerosols with reduced stain problem, deodorant comprising the same and use of the deodorant HENKEL AG & CO. KGAA (DE) 2022-05-10 US disclosed
US-11090237-B2 Deodorant cosmetic compositions comprising calcium silicate and sodium bicarbonate HENKEL AG & CO. KGAA (DE) 2021-08-17 US disclosed
US-11045399-B2 Residue-minimized antiperspirant composition with improved skin feel HENKEL AG & CO. KGAA (DE) 2021-06-29 US disclosed
US-20210093521-A1 ANTIBACTERIAL ACTIVITY BY MG COMPLEX IN DEODORANT EMULSION FOR AEROSOLS, DEODORANT INCLUDING THE SAME AND USE OF THE DEODORANT HENKEL AG & CO. KGAA (DE) 2021-04-01 US disclosed
US-20210093522-A1 DEO EMULSION FOR AEROSOLS WITH REDUCED STAIN PROBLEM, DEODORANT COMPRISING THE SAME AND USE OF THE DEODORANT HENKEL AG & CO. KGAA (DE) 2021-04-01 US disclosed
WO-2010031657-A2 USE OF UREA DERIVATIVES AND PHENACYLTHIAZOLIUM SALTS FOR THE TREATMENT OF BODY ODOUR HENKEL AG & CO. KGAA (DE) 2010-03-25 WO disclosed
WO-2010009977-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A SPRAY HENKEL AG & CO. KGAA (DE) 2010-01-28 WO disclosed
WO-2010009976-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A NON-AEROSOL HENKEL AG & CO. KGAA (DE) 2010-01-28 WO disclosed
WO-2009083547-A2 WATER-FREE ANTIPERSPIRANT SPRAYS WITH IMPROVED SUBSTANCE RELEASE HENKEL AG & CO. KGAA (DE) 2009-07-09 WO disclosed
WO-2008155391-A2 COSMETIC STICK BASED ON A CONGEALED OIL-IN-WATER DISPERSION/EMULSION HENKEL AG & CO. KGAA (DE) 2008-12-24 WO disclosed
WO-2008155382-A2 COSMETIC STICK BASED ON A CONGEALED OIL-IN-WATER DISPERSION/EMULSION HAVING A HYDROGEL FORMER HENKEL AG & CO. KGAA (DE) 2008-12-24 WO disclosed
US-7459460-B2 Trisubstituted heteroaromatic compounds as calcium sensing receptor modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2008-12-02 US disclosed