SCHEMBL344690

SCHEMBL344690

CCC(CO)Cc1ccc(Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.48
SLC6A3 Q01959 1/20 0.48
SLC6A4 P31645 1/20 0.47
PPARG P37231 4/20 0.40
EPHX2 P34913 2/20 0.40
CTSC P53634 1/20 0.40
PPARA Q07869 3/20 0.39
TRPA1 O75762 2/20 0.38
ACACB O00763 1/20 0.37
HTT P42858 1/20 0.37
IDO1 P14902 1/20 0.37
P2RX3 P56373 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
ROCK2 O75116 1/20 0.35
PRKACA P17612 1/20 0.35
RPS6KB1 P23443 1/20 0.35
IRAK1 P51617 1/20 0.35
PRKX P51817 1/20 0.35
LIMK1 P53667 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6153738 0.87 SLC6A4 (0.54) SLC6A2SLC6A3SLC6A4PPARGPPARA
SCHEMBL24827443 0.87 SLC6A2 (0.56) SLC6A2SLC6A3SLC6A4PPARGEPHX2
SCHEMBL12512917 0.82 ESR1 (0.55) SLC6A2SLC6A3ESR1ESR2
SCHEMBL345256 0.82 TRPA1 (0.39) SLC6A4TRPA1ACACBIDO1ESR1
SCHEMBL14003410 0.80 TRPA1 (0.58) PPARGEPHX2TRPA1IDO1ESR1
SCHEMBL31648185 0.80 SLC6A4 (0.52) SLC6A2SLC6A3SLC6A4PPARGPPARA
SCHEMBL24294405 0.80 SLC6A2 (0.48) SLC6A2SLC6A3SLC6A4PPARGEPHX2
SCHEMBL11570604 0.80 CYP1A2 (0.44) SLC6A4TRPA1IDO1ESR1ESR2
SCHEMBL344081 0.79 PNMT (0.53) SLC6A2SLC6A3SLC6A4IDO1
SCHEMBL2604925 0.79 TRPA1 (0.55) SLC6A2SLC6A3SLC6A4TRPA1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210069071-A1 COSMETIC SOAP GEL STICKS WITH IMPROVED MANUFACTURABILITY HENKEL AG & CO. KGAA (DE) 2021-03-11 US claimed
EP-2453867-A2 COSMETIC AND DERMATOLOGICAL TOPICAL COMPOSITIONS HAVING A HAIR GROWTH-MINIMISING OR HAIR GROWTH-INHIBITING EFFECT Henkel AG & Co. KGaA (DE) 2012-05-23 EP claimed
EP-2349185-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A SPRAY Henkel AG & Co. KGaA (DE) 2011-08-03 EP claimed
EP-2349184-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A NON-AEROSOL Henkel AG & Co. KGaA (DE) 2011-08-03 EP claimed
WO-2011006689-A2 COSMETIC AND DERMATOLOGICAL TOPICAL COMPOSITIONS HAVING A HAIR GROWTH-MINIMISING OR HAIR GROWTH-INHIBITING EFFECT HENKEL AG & CO. KGAA (DE) 2011-01-20 WO claimed
WO-2010009976-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A NON-AEROSOL HENKEL AG & CO. KGAA (DE) 2010-01-28 WO claimed
WO-2010009977-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A SPRAY HENKEL AG & CO. KGAA (DE) 2010-01-28 WO claimed
US-11504309-B2 Deo emulsion for aerosols, deodorant comprising the same and use of the deodorant HENKEL AG & CO. KGAA (DE) 2022-11-22 US disclosed
US-11324675-B2 Deo emulsion for aerosols with reduced stain problem, deodorant comprising the same and use of the deodorant HENKEL AG & CO. KGAA (DE) 2022-05-10 US disclosed
US-11090237-B2 Deodorant cosmetic compositions comprising calcium silicate and sodium bicarbonate HENKEL AG & CO. KGAA (DE) 2021-08-17 US disclosed
US-11045399-B2 Residue-minimized antiperspirant composition with improved skin feel HENKEL AG & CO. KGAA (DE) 2021-06-29 US disclosed
US-20210093520-A1 DEO EMULSION FOR AEROSOLS, DEODORANT COMPRISING THE SAME AND USE OF THE DEODORANT HENKEL AG & CO. KGAA (DE) 2021-04-01 US disclosed
US-20210093521-A1 ANTIBACTERIAL ACTIVITY BY MG COMPLEX IN DEODORANT EMULSION FOR AEROSOLS, DEODORANT INCLUDING THE SAME AND USE OF THE DEODORANT HENKEL AG & CO. KGAA (DE) 2021-04-01 US disclosed
EP-2167018-A2 COSMETIC STICK BASED ON A CONGEALED OIL-IN-WATER DISPERSION/EMULSION Henkel AG & Co. KGaA (DE) 2010-03-31 EP disclosed
WO-2010031657-A2 USE OF UREA DERIVATIVES AND PHENACYLTHIAZOLIUM SALTS FOR THE TREATMENT OF BODY ODOUR HENKEL AG & CO. KGAA (DE) 2010-03-25 WO disclosed
WO-2010009976-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A NON-AEROSOL HENKEL AG & CO. KGAA (DE) 2010-01-28 WO disclosed
WO-2010009977-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A SPRAY HENKEL AG & CO. KGAA (DE) 2010-01-28 WO disclosed
WO-2009083547-A2 WATER-FREE ANTIPERSPIRANT SPRAYS WITH IMPROVED SUBSTANCE RELEASE HENKEL AG & CO. KGAA (DE) 2009-07-09 WO disclosed
WO-2008155382-A2 COSMETIC STICK BASED ON A CONGEALED OIL-IN-WATER DISPERSION/EMULSION HAVING A HYDROGEL FORMER HENKEL AG & CO. KGAA (DE) 2008-12-24 WO disclosed
WO-2008155391-A2 COSMETIC STICK BASED ON A CONGEALED OIL-IN-WATER DISPERSION/EMULSION HENKEL AG & CO. KGAA (DE) 2008-12-24 WO disclosed