Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.51 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 2/20 | 0.42 |
| ▸ | GIPR | P48546 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13109543 | 0.99 | ITGB3 (0.51) | ITGB3ITGA2BCPB1MEN1KMT2A | |
| SCHEMBL3451821 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BCPB1MEN1KMT2A | |
| SCHEMBL3453232 | 0.90 | ITGB3 (0.48) | ITGB3ITGA2BCPB1MEN1KMT2A | |
| SCHEMBL5159499 | 0.89 | ITGB3 (0.49) | ITGB3ITGA2BCPB1MEN1KMT2A | |
| SCHEMBL3454047 | 0.83 | CPB1 (0.46) | ITGB3ITGA2BCPB1MEN1KMT2A | |
| SCHEMBL3451457 | 0.82 | ITGB3 (0.47) | ITGB3ITGA2BCPB1MEN1KMT2A | |
| SCHEMBL3452512 | 0.82 | CPB1 (0.46) | ITGB3ITGA2BCPB1MEN1KMT2A | |
| SCHEMBL3451819 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2BCPB1MEN1KMT2A | |
| SCHEMBL27681519 | 0.82 | ITGB3 (0.53) | ITGB3ITGA2BCPB1MEN1KMT2A | |
| SCHEMBL3452899 | 0.81 | CPB1 (0.43) | ITGB3ITGA2BCPB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820704-B2 | Substituted heteroaryl derivatives, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-20050261294-A1 | Substituted heteroaryl derivatives, compositions, and methods of use | VTVX HOLDINGS I LLC | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261294-A1 | Substituted heteroaryl derivatives, compositions, and methods of use | MC5R, MC3R, MC4R | ITGB3 1281/4885ITGA2B 1854/4885CPB1 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.